Gene

ago3a

ID

ZDB-GENE-051107-16

Name

argonaute RISC catalytic component 3a

Symbol

ago3a Nomenclature History

Previous Names

Ago3a (1)
eif2c3a
sb:eu275
sb:eu416

Type

protein_coding_gene

Location

Chr: 16 Mapping Details/Browsers

Description

Predicted to have miRNA binding activity. Predicted to be involved in miRNA mediated inhibition of translation and regulation of stem cell proliferation. Predicted to localize to P-body and RISC complex. Is expressed in fin; integument; nervous system; and pleuroperitoneal region. Orthologous to human AGO3 (argonaute RISC catalytic component 3).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

8 figures from 2 publications

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

eu275 (3 images)
eu416 (1 image)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With ago3a Human Ortholog

No data available

Associated With ago3a Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR003100	PAZ domain
Domain	IPR003165	Piwi domain
Domain	IPR014811	Argonaute, linker 1 domain
Domain	IPR032472	Argonaute linker 2 domain
Domain	IPR032473	Protein argonaute, Mid domain
Domain	IPR032474	Protein argonaute, N-terminal
Domain	IPR045246	Argonaute-like, PIWI domain
Family	IPR028603	Protein argonaute-3
Homologous_superfamily	IPR012337	Ribonuclease H-like superfamily
Homologous_superfamily	IPR036085	PAZ domain superfamily
Homologous_superfamily	IPR036397	Ribonuclease H superfamily

Domain Details Per Protein

Protein	Length	Argonaute-like, PIWI domain	Argonaute, linker 1 domain	Argonaute linker 2 domain	PAZ domain	PAZ domain superfamily	Piwi domain	Protein argonaute-3	Protein argonaute, Mid domain	Protein argonaute, N-terminal	Ribonuclease H-like superfamily	Ribonuclease H superfamily
UniProtKB:F1Q7S8 InterPro	860
UniProtKB:A0A8M6YSQ3 InterPro	476
UniProtKB:A0A8M3ATW3 InterPro	860
UniProtKB:K4I722 InterPro	867

Transcripts

Genome Browsers

NCBI

Type	Name	Annotation Method	Has Havana Data	Length (nt)	Analysis
mRNA	ago3a-201 (1) Ensembl	Ensembl		3,073 nt	Select Tool ZFIN BLAST

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations