Gene
igl4v8
- ID
- ZDB-GENE-051013-6
- Name
- immunoglobulin light 4 variable 8
- Symbol
- igl4v8 Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 25 Mapping Details/Browsers
- Description
- Predicted to be located in plasma membrane. Orthologous to several human genes including IGKV1-27 (immunoglobulin kappa variable 1-27); IGKV1-39 (immunoglobulin kappa variable 1-39); and IGKV1-5 (immunoglobulin kappa variable 1-5).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
No data available
No data available
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR003006 | Immunoglobulin/major histocompatibility complex, conserved site |
| Domain | IPR003597 | Immunoglobulin C1-set |
| Domain | IPR003599 | Immunoglobulin domain subtype |
| Domain | IPR007110 | Immunoglobulin-like domain |
| Domain | IPR013106 | Immunoglobulin V-set domain |
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Domain Details Per Protein
| Protein | Additional Resources | Length | Immunoglobulin C1-set | Immunoglobulin domain subtype | Immunoglobulin-like domain | Immunoglobulin-like domain superfamily | Immunoglobulin-like fold | Immunoglobulin/major histocompatibility complex, conserved site | Immunoglobulin Variable Light Chain | Immunoglobulin V-set domain |
|---|---|---|---|---|---|---|---|---|---|---|
| UniProtKB:A0AB32TID1 | InterPro | 235 |
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| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
igl4v8-201
(1)
|
Ensembl | 893 nt |
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Interactions and Pathways
No data available
Plasmids
No data available
No data available
| Relationship | Marker Type | Marker | Accession Numbers | Citations |
|---|---|---|---|---|
| Contained in | BAC | DKEY-234I14 | Zimmerman et al., 2011 |
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| Type | Accession # | Sequence | Length (nt/aa) | Analysis |
|---|---|---|---|---|
| RNA | RefSeq:XM_068217596 (1) | 827 nt | ||
| Genomic | GenBank:CU207301 (1) | 174391 nt | ||
| Polypeptide | UniProtKB:A0AB32TID1 (1) | 235 aa |
No data available
- Wu, P., Zhou, S., Su, Z., Liu, C., Zeng, F., Pang, H., Xie, M., Jian, J. (2020) Functional characterization of T3SS C-ring component VscQ and evaluation of its mutant as a live attenuated vaccine in zebrafish (Danio rerio) model. Fish & shellfish immunology. 104:123-132
- Zhang, L., Liu, C., Zhou, X., Xie, Y., Su, L., Geng, Q., Liu, B., Liu, S. (2016) Transgenic overexpression of BAFF regulates the expression of immune-related genes in zebrafish, Danio rerio. Journal of genetics. 95:751-760
- Zimmerman, A.M., Romanowski, K.E., and Maddox, B.J. (2011) Targeted annotation of immunoglobulin light chain (IgL) genes in zebrafish from BAC clones reveals kappa-like recombining/deleting elements within IgL constant regions. Fish & shellfish immunology. 31(5):697-703
- Yoder, J.A., Turner, P.M., Wright, P.D., Wittamer, V., Bertrand, J.Y., Traver, D., and Litman, G.W. (2010) Developmental and tissue-specific expression of NITRs. Immunogenetics. 62(2):117-122
- Haire, R.N., Rast, J.P., Litman, R.T., and Litman, G.W. (2000) Characterization of three isotypes of immunoglobulin light chains and T-cell antigen receptor a in zebrafish. Immunogenetics. 51(11):915-923
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