Gene

rsad2

ID
ZDB-GENE-050913-129
Name
radical S-adenosyl methionine domain containing 2
Symbol
rsad2 Nomenclature History
Previous Names
  • si:ch211-276e8.2
  • vig1 (1)
  • viperin (1)
  • zgc:112342
Type
protein_coding_gene
Location
Chr: 17 Mapping Details/Browsers
Description
Predicted to have 4 iron, 4 sulfur cluster binding activity; catalytic activity; and metal ion binding activity. Involved in response to virus. Predicted to localize to endoplasmic reticulum and endoplasmic reticulum membrane. Human ortholog(s) of this gene implicated in respiratory syncytial virus infectious disease. Orthologous to human RSAD2 (radical S-adenosyl methionine domain containing 2).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
12 figures from 6 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With rsad2 Human Ortholog
No data available
Associated With rsad2 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR006638 Elp3/MiaA/NifB-like, radical SAM core domain
Domain IPR007197 Radical SAM
Family IPR026372 S-adenosylmethionine-dependent nucleotide dehydratase RSAD2
Family IPR051196 RSAD2 and Viperin antiviral
Homologous_superfamily IPR013785 Aldolase-type TIM barrel
Domain Details Per Protein
Protein Length Aldolase-type TIM barrel Elp3/MiaA/NifB-like, radical SAM core domain Radical SAM RSAD2 and Viperin antiviral S-adenosylmethionine-dependent nucleotide dehydratase RSAD2
UniProtKB:Q5RH95 359
UniProtKB:B2GP21 359
Transcripts
Genome Browsers
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA rsad2-201 (1) Ensembl 1,623 nt
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations