Gene

eml2

ID

ZDB-GENE-050706-71

Name

EMAP like 2

Symbol

eml2 Nomenclature History

Previous Names

wu:fq15f04
zgc:110445

Type

protein_coding_gene

Location

Chr: 15 Mapping Details/Browsers

Description

Predicted to have microtubule binding activity. Predicted to be involved in microtubule cytoskeleton organization. Predicted to colocalize with mitotic spindle. Is expressed in several structures, including Kupffer's vesicle; forerunner cell group; hatching gland; lens placode; and nervous system. Orthologous to human EML2 (EMAP like 2).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

17 figures from 2 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

IMAGE:7158350 (16 images)
IMAGE:7148412 (21 images)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With eml2 Human Ortholog

No data available

Associated With eml2 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Conserved_site	IPR005108	HELP motif
Domain	IPR049040	Regulator of MON1-CCZ1 complex, N-terminal
Family	IPR050630	WD repeat Echinoderm Microtubule-associated Protein-like
Homologous_superfamily	IPR011047	Quinoprotein alcohol dehydrogenase-like superfamily
Homologous_superfamily	IPR015943	WD40/YVTN repeat-like-containing domain superfamily
Homologous_superfamily	IPR036322	WD40-repeat-containing domain superfamily
Repeat	IPR001680	WD40 repeat

Domain Details Per Protein

Protein	Length	HELP motif	Quinoprotein alcohol dehydrogenase-like superfamily	Regulator of MON1-CCZ1 complex, N-terminal	WD40 repeat	WD40-repeat-containing domain superfamily	WD40/YVTN repeat-like-containing domain superfamily	WD repeat Echinoderm Microtubule-associated Protein-like
UniProtKB:A0A8M2B400 InterPro	648
UniProtKB:A0A8M3AHE0 InterPro	784
UniProtKB:Q4KMH7 InterPro	805

Transcripts

Genome Browsers

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	eml2-201 (1) Ensembl	Ensembl	2,960 nt	Select Tool ZFIN BLAST
mRNA	eml2-202 (1) Ensembl	Ensembl	2,878 nt	Select Tool
mRNA	eml2-204 (1) Ensembl	Ensembl	3,211 nt	Select Tool ZFIN BLAST
mRNA	eml2-205 (1) Ensembl	Ensembl	5,354 nt	Select Tool ZFIN BLAST
ncRNA	eml2-002 (1) Ensembl	Ensembl	600 nt	Select Tool

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations