Gene

gigyf2

ID

ZDB-GENE-050706-185

Name

GRB10 interacting GYF protein 2

Symbol

gigyf2 Nomenclature History

Previous Names

gigfy2 (1)
fb57e02
im:6911549 (1)
wu:fb57e02 (1)
zgc:111944 (1)

Type

protein_coding_gene

Location

Chr: 2 Mapping Details/Browsers

Description

Human ortholog(s) of this gene implicated in Parkinson's disease. Is expressed in blastoderm; blastodisc; brain; and somite. Orthologous to human GIGYF2 (GRB10 interacting GYF protein 2).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

3 figures from 3 publications

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Thisse Expression Data

IMAGE:6911549 (1 image)

Wild Type Expression Summary

Phenotype

All Phenotype Data: 3 figures from 2 publications
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With gigyf2 Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
		{Parkinson disease 11}	607688

Associated With gigyf2 Via Experimental Models

Human Disease	Fish	Conditions	Citations
schizophrenia	gigyf2^a273/a273	standard conditions	Thyme et al., 2019

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR003169	GYF domain
Homologous_superfamily	IPR035445	GYF-like domain superfamily

Domain Details Per Protein

Protein	Length	GYF domain	GYF-like domain superfamily
UniProtKB:B0S7J5 InterPro	1329
UniProtKB:Q4KME6 InterPro	1329
UniProtKB:A0A8M6Z920 InterPro	1324

Transcripts

Genome Browsers

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	gigyf2-201 (1) Ensembl	Havana	4696 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations