Gene
cyp3a65
- ID
- ZDB-GENE-050604-1
- Name
- cytochrome P450, family 3, subfamily A, polypeptide 65
- Symbol
- cyp3a65 Nomenclature History
- Previous Names
-
- zgc:123110
- Type
- protein_coding_gene
- Location
- Chr: 1 Mapping Details/Browsers
- Description
- Predicted to enable steroid hydroxylase activity. Acts upstream of or within response to xenobiotic stimulus. Predicted to be located in membrane. Is expressed in several structures, including digestive system; eye; gill; heart; and ovary. Human ortholog(s) of this gene implicated in B-lymphoblastic leukemia/lymphoma; acute lymphoblastic leukemia; chronic myeloid leukemia; essential hypertension; and familial Mediterranean fever. Orthologous to several human genes including CYP3A7-CYP3A51P (CYP3A7-CYP3A51P readthrough); CYP3A43 (cytochrome P450 family 3 subfamily A member 43); and CYP3A5 (cytochrome P450 family 3 subfamily A member 5).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 29 figures from 12 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Cytochrome P450 | Cytochrome P450 3A | Cytochrome P450, conserved site | Cytochrome P450, E-class, group I | Cytochrome P450 superfamily |
|---|---|---|---|---|---|---|
|
UniProtKB:Q32LT1
|
517 |
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
cyp3a65-201
(1)
|
Ensembl | 2,020 nt |
Interactions and Pathways
No data available
Plasmids
No data available