Gene
il12ba
- ID
- ZDB-GENE-050525-3
- Name
- interleukin 12Ba
- Symbol
- il12ba Nomenclature History
- Previous Names
-
- il-12p40.a (1)
- il12b
- zgc:152789
- Type
- protein_coding_gene
- Location
- Chr: 14 Mapping Details/Browsers
- Description
- Predicted to enable cytokine binding activity and cytokine receptor activity. Predicted to be involved in cytokine-mediated signaling pathway. Predicted to be located in extracellular space. Predicted to be part of receptor complex. Predicted to be active in external side of plasma membrane. Is expressed in dendritic cell and intestine. Human ortholog(s) of this gene implicated in asthma; chronic obstructive pulmonary disease; immunodeficiency 29; and salmonellosis. Orthologous to human IL12B (interleukin 12B).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 8 figures from 7 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| immunodeficiency 29 | Alliance | Immunodeficiency 29, mycobacteriosis | 614890 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Fibronectin type III superfamily | Immunoglobulin-like fold | Interleukin-12 beta | Interleukin-12 beta, central domain |
|---|---|---|---|---|---|
|
UniProtKB:Q6F3Q9
|
324 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
il12ba-201
(1)
|
Ensembl | 1,343 nt | ||
| mRNA |
il12ba-202
(1)
|
Ensembl | 1,107 nt | ||
| mRNA |
il12ba-203
(1)
|
Ensembl | 977 nt |
Interactions and Pathways
No data available
Plasmids
No data available