ZFIN ID: ZDB-GENE-050522-559
Gene Name: cathepsin S, ortholog2, tandem duplicate 1
Gene Symbol: ctss2.1
Previous Names: ctssb.1 (1), ctssb1 (1), zf-a41, fc38f10, fc47h06, im:6797184, ns:zf-a41, wu:fc38f10, wu:fc47h06, wu:fi17f10, zgc:112226, zgc:112369, zgc:123302
Location: Chr: 16 Mapping Details/Browsers
Nomenclature History
GENE EXPRESSION
All Expression Data: Fig. 2 from Gao et al., 2014
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTSNo data available
PHENOTYPE No data available
DISEASE ASSOCIATED WITH ctss2.1 HUMAN ORTHOLOGNo data available
GENE ONTOLOGY
Ontology GO Term
Biological Process proteolysis (more)
Cellular Component extracellular space (more)
Molecular Function cysteine-type peptidase activity (more)
GO Terms (all 11)
PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR000169 (1)
  • InterPro:IPR000668 (1)
  • InterPro:IPR013128 (1)
  • InterPro:IPR013201 (1)
  • InterPro:IPR025660 (1)
  • InterPro:IPR025661 (1)
  • PROSITE:PS00139 (1)
  • PROSITE:PS00639 (1)
  • PROSITE:PS00640 (1)
  • Pfam:PF00112 (1)
  • Pfam:PF08246 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA ctss2.1-001 (1) 1227
    ncRNA ctss2.1-002 (1) 803
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYSNo data available
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM ctss2.1 No data available
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS
    ctss2.1Contained in: [BAC] CH211-113G11 (1) (order this), DKEY-30O16 (1) (order this)
    ctss2.1Contains: [SNP] rs3728791 (1), rs3728792 (1), rs3728793 (1), rs3728794 (1), rs3728795 (1), rs3728796 (1), rs3728797 (1)
    ctss2.1Encodes: [EST] fc38f10, fc47h06, fi17f10 (1), IMAGE:6797184 (1), zf-a41
    [cDNA] MGC:112226 (1), MGC:112369 (1) (order this), MGC:123302 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001024409 (1) 1244bp
    Genomic GenBank:BX248517 (1) 201353bp Blast at MegaBLAST
    Polypeptide UniProtKB:Q502A6 (1) 330aa
    Sequence Clusters UniGene:75553 (1)
    Sequence Information (all 30)
    OTHER ctss2.1 GENE PAGES
  • Gene:554157 (1)
  • VEGA:OTTDARG00000034140 (1)
  • Ensembl(GRCz10):ENSDARG00000074656 (1)
  • ORTHOLOGY for ctss2.1 (Chr: 16)
    Species Symbol Chromosome Accession # Evidence
    Human CTSS 1
  • Gene:1520
  • OMIM:116845
  • HGNC:2545
  • Amino acid sequence comparison (2)
    Conserved genome location (synteny) (1)
    Phylogenetic tree (2)
    Mouse Ctss 3
  • MGI:107341
  • Gene:13040
  • Amino acid sequence comparison (2)
    Conserved genome location (synteny) (1)
    Phylogenetic tree (2)
    Download Curated Orthology
    Orthology Note
    This gene and ctssb.2 (ZDB-GENE-050626-55) are located next to each other in the genome and appear to be the result of a tandem duplication. The tandem duplicates appear to be the orthologs of human CTSS and mouse Ctss based on amino acid identity and conserved location.
    CITATIONS (25)