Gene

gtf2a2

ID

ZDB-GENE-050522-513

Name

general transcription factor IIA, 2

Symbol

gtf2a2 Nomenclature History

Previous Names

zgc:110584

Type

protein_coding_gene

Location

Chr: 7 Mapping Details/Browsers

Description

Predicted to have TBP-class protein binding activity and transcription coactivator activity. Predicted to be involved in RNA polymerase II preinitiation complex assembly; positive regulation of DNA-binding transcription factor activity; and positive regulation of transcription by RNA polymerase II. Predicted to localize to transcription factor TFIIA complex. Orthologous to human GTF2A2 (general transcription factor IIA subunit 2).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

1 figure from Thisse et al., 2004

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Thisse Expression Data

MGC:110584 (1 image)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With gtf2a2 Human Ortholog

No data available

Associated With gtf2a2 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR015871	Transcription initiation factor IIA, gamma subunit, C-terminal
Domain	IPR015872	Transcription initiation factor IIA, gamma subunit, N-terminal
Family	IPR003194	Transcription initiation factor IIA, gamma subunit
Homologous_superfamily	IPR009083	Transcription factor IIA, alpha-helical domain
Homologous_superfamily	IPR009088	Transcription factor IIA, beta-barrel