Gene
txndc12
- ID
- ZDB-GENE-050522-497
- Name
- thioredoxin domain containing 12 (endoplasmic reticulum)
- Symbol
- txndc12 Nomenclature History
- Previous Names
-
- wu:fc47c08
- zgc:110680 (1)
- Type
- protein_coding_gene
- Location
- Chr: 2 Mapping Details/Browsers
- Description
- Enables protein-disulfide reductase (NAD(P)) activity. Acts upstream of or within cellular response to DNA damage stimulus and detoxification of hydrogen peroxide. Predicted to be active in endoplasmic reticulum. Is expressed in several structures, including brain; digestive system; immune system; pectoral fin bud; and ventricular zone. Orthologous to human TXNDC12 (thioredoxin domain containing 12).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 5 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- IMAGE:6899694 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Anterior Gradient and Thioredoxin Domain | ERp19 | Thioredoxin, conserved site | Thioredoxin domain | Thioredoxin-like superfamily |
|---|---|---|---|---|---|---|
|
UniProtKB:Q503D8
|
172 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
txndc12-201
(1)
|
Ensembl | 2,308 nt |
Interactions and Pathways
No data available
Plasmids
No data available