Gene

impa2

ID
ZDB-GENE-050522-349
Name
inositol monophosphatase 2
Symbol
impa2 Nomenclature History
Previous Names
  • zgc:110201
Type
protein_coding_gene
Location
Chr: 24 Mapping Details/Browsers
Description
Predicted to have inositol monophosphate 1-phosphatase activity. Predicted to be involved in inositol metabolic process; inositol phosphate dephosphorylation; and signal transduction. Human ortholog(s) of this gene implicated in bipolar disorder and schizophrenia. Is expressed in brain; central nervous system; epiphysis; optic vesicle; and retina. Orthologous to human IMPA2 (inositol monophosphatase 2).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
6 figures from Thisse et al., 2004
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
1 Figure from Stratman et al., 2020
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With impa2 Human Ortholog
No data available
Associated With impa2 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Binding_site IPR020583 Inositol monophosphatase, metal-binding site
Conserved_site IPR020550 Inositol monophosphatase, conserved site
Family IPR000760 Inositol monophosphatase-like
Family IPR020552 Inositol monophosphatase, lithium-sensitive
Family IPR033942 Inositol monophosphatase
Domain Details Per Protein
Protein Length Inositol monophosphatase Inositol monophosphatase, conserved site Inositol monophosphatase-like Inositol monophosphatase, lithium-sensitive Inositol monophosphatase, metal-binding site
UniProtKB:A0A8M9P5W4 220
UniProtKB:Q503S9 275
Transcripts
Genome Browsers
No data available
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations