Gene
twf2b
- ID
- ZDB-GENE-050522-238
- Name
- twinfilin actin-binding protein 2b
- Symbol
- twf2b Nomenclature History
- Previous Names
-
- si:ch211-14i3.4
- zgc:112092
- Type
- protein_coding_gene
- Location
- Chr: 11 Mapping Details/Browsers
- Description
- Predicted to enable actin filament binding activity and actin monomer binding activity. Predicted to be involved in actin filament depolymerization; negative regulation of actin filament polymerization; and regulation of plasma membrane bounded cell projection organization. Predicted to act upstream of or within negative regulation of actin filament polymerization. Predicted to be located in cytoskeleton. Predicted to be active in actin filament and myofibril. Is expressed in lateral line; otic placode; otic vesicle; and posterior lateral line system. Orthologous to human TWF2 (twinfilin actin binding protein 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 8 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:112092 (10 images)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Actin-depolymerising factor homology domain | ADF-H/Gelsolin-like domain superfamily | Twinfilin |
|---|---|---|---|---|
|
UniProtKB:Q502J8
|
364 | |||
|
UniProtKB:E7F2D6
|
369 |
Interactions and Pathways
No data available
Plasmids
No data available