Gene
prep
- ID
- ZDB-GENE-050522-14
- Name
- prolyl endopeptidase
- Symbol
- prep Nomenclature History
- Previous Names
-
- im:7140031
- zgc:110670
- Type
- protein_coding_gene
- Location
- Chr: 20 Mapping Details/Browsers
- Description
- Predicted to enable oligopeptidase activity. Predicted to act upstream of or within proteolysis. Predicted to be active in cytosol. Orthologous to human PREP (prolyl endopeptidase).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Thisse et al., 2004
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- IMAGE:7140031 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
| Allele | Type | Localization | Consequence | Mutagen | Supplier |
|---|---|---|---|---|---|
| la021711Tg | Transgenic insertion | Unknown | Unknown | DNA | |
| sa3079 | Allele with one point mutation | Unknown | Premature Stop | ENU | |
| sa5677 | Allele with one point mutation | Unknown | Premature Stop | ENU | |
| sa23810 | Allele with one point mutation | Unknown | Splice Site | ENU | |
| sa43533 | Allele with one point mutation | Unknown | Premature Stop | ENU |
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Show
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Active_site | IPR002471 | Peptidase S9, serine active site |
| Domain | IPR001375 | Peptidase S9, prolyl oligopeptidase, catalytic domain |
| Domain | IPR023302 | Peptidase S9A, N-terminal domain |
| Family | IPR002470 | Peptidase S9A, prolyl oligopeptidase |
| Family | IPR051167 | Prolyl oligopeptidase and macrocyclase |
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Domain Details Per Protein
| Protein | Length | Alpha/Beta hydrolase fold | Peptidase S9A, N-terminal domain | Peptidase S9A, prolyl oligopeptidase | Peptidase S9, prolyl oligopeptidase, catalytic domain | Peptidase S9, serine active site | Prolyl oligopeptidase and macrocyclase |
|---|---|---|---|---|---|---|---|
|
UniProtKB:Q503E2
|
709 |
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- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available
No data available