Gene

abca5

ID

ZDB-GENE-050517-5

Name

ATP-binding cassette, sub-family A (ABC1), member 5

Symbol

abca5 Nomenclature History

Previous Names

zgc:163009 (1)

Type

protein_coding_gene

Location

Chr: 12 Mapping Details/Browsers

Description

Predicted to enable ATPase-coupled transmembrane transporter activity and lipid transporter activity. Predicted to be involved in lipid transport. Predicted to act upstream of or within transmembrane transport. Predicted to be located in membrane. Predicted to be active in intracellular membrane-bounded organelle. Is expressed in basal plate midbrain region; mucus secreting cell; nervous system; pronephric duct; and pronephric mesoderm. Orthologous to several human genes including ABCA5 (ATP binding cassette subfamily A member 5).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

6 figures from Thisse et al., 2004

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

IMAGE:7165803 (19 images)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With abca5 Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
		?Hypertrichosis, congenital generalized, with gingival hyperplasia	135400

Associated With abca5 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Conserved_site	IPR017871	ABC transporter-like, conserved site
Domain	IPR003439	ABC transporter-like, ATP-binding domain
Domain	IPR003593	AAA+ ATPase domain
Domain	IPR013525	ABC-2 type transporter, transmembrane domain
Family	IPR026082	ABC transporter A
Homologous_superfamily	IPR027417	P-loop containing nucleoside triphosphate hydrolase