Gene

abcc3

ID

ZDB-GENE-050517-16

Name

ATP-binding cassette, sub-family C (CFTR/MRP), member 3

Symbol

abcc3 Nomenclature History

Previous Names

si:ch211-176g6.3
si:ch73-359p15.1
wu:fb94e12

Type

protein_coding_gene

Location

Chr: 12 Mapping Details/Browsers

Description

Predicted to enable ATPase-coupled transmembrane transporter activity. Predicted to be involved in transmembrane transport. Predicted to be located in plasma membrane. Predicted to be active in membrane. Orthologous to human ABCC3 (ATP binding cassette subfamily C member 3).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

No data available

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With abcc3 Human Ortholog

No data available

Associated With abcc3 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Conserved_site	IPR017871	ABC transporter-like, conserved site
Domain	IPR003439	ABC transporter-like, ATP-binding domain
Domain	IPR003593	AAA+ ATPase domain
Domain	IPR011527	ABC transporter type 1, transmembrane domain
Family	IPR005292	Multi drug resistance-associated protein
Family	IPR050173	ATP-binding cassette transporter C-like
Homologous_superfamily	IPR027417	P-loop containing nucleoside triphosphate hydrolase
Homologous_superfamily	IPR036640	ABC transporter type 1, transmembrane domain superfamily

Domain Details Per Protein

Protein	Length	AAA+ ATPase domain	ABC transporter-like, ATP-binding domain	ABC transporter-like, conserved site	ABC transporter type 1, transmembrane domain	ABC transporter type 1, transmembrane domain superfamily	ATP-binding cassette transporter C-like	Multi drug resistance-associated protein	P-loop containing nucleoside triphosphate hydrolase
UniProtKB:A0A8M3AXY3 InterPro	1540
UniProtKB:A0A8M3AY17 InterPro	1140
UniProtKB:A0A8M3BDY5 InterPro	1107
UniProtKB:A0A8M3B758 InterPro	1539
UniProtKB:A0A8M3B4C9 InterPro	1539

Transcripts

Genome Browsers

NCBI

Ensembl

ZFIN

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	abcc3-202 (1) Ensembl	Ensembl	898 nt	Select Tool ZFIN BLAST
mRNA	abcc3-203 (1) Ensembl	Ensembl	5,130 nt	Select Tool ZFIN BLAST
ncRNA	abcc3-003 (1) Ensembl	Ensembl	633 nt	Select Tool ZFIN BLAST

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance

Citations