Gene

eps8l1b

ID
ZDB-GENE-050506-143
Name
EPS8 signaling adaptor L1b
Symbol
eps8l1b Nomenclature History
Previous Names
  • im:7147678 (1)
  • si:ch73-70c5.1
Type
protein_coding_gene
Location
Chr: 24 Mapping Details/Browsers
Description
Predicted to contribute to Rac guanyl-nucleotide exchange factor activity. Predicted to be involved in Rho protein signal transduction; positive regulation of ruffle assembly; and regulation of Rho protein signal transduction. Predicted to localize to ruffle membrane. Orthologous to human EPS8L1 (EPS8 like 1).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
1 figure from Thisse et al., 2004
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With eps8l1b Human Ortholog
No data available
Associated With eps8l1b Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR001452 SH3 domain
Domain IPR041418 SAM domain
Family IPR039801 Epidermal growth factor receptor kinase substrate 8-like
Homologous_superfamily IPR013761 Sterile alpha motif/pointed domain superfamily
Homologous_superfamily IPR036028 SH3-like domain superfamily
Domain Details Per Protein
Protein Length Epidermal growth factor receptor kinase substrate 8-like SAM domain SH3 domain SH3-like domain superfamily Sterile alpha motif/pointed domain superfamily
UniProtKB:E7F1L9 505
UniProtKB:A0A8M2BI52 649
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Citations