Gene
fermt2
- ID
- ZDB-GENE-050506-132
- Name
- FERM domain containing kindlin 2
- Symbol
- fermt2 Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 17 Mapping Details/Browsers
- Description
- Predicted to have lipid binding activity. Involved in cell migration; circulatory system development; and cytoskeleton organization. Localizes to intercalated disc. Is expressed in several structures, including forerunner cell group; head mesenchyme; heart; myotome; and notochord. Orthologous to human FERMT2 (fermitin family member 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 7 figures from 3 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- IMAGE:7145859 (13 images)
Wild Type Expression Summary
- All Phenotype Data
- 10 figures from 4 publications
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Type | InterPro ID | Name |
---|---|---|
Domain | IPR001849 | Pleckstrin homology domain |
Domain | IPR019748 | FERM central domain |
Domain | IPR019749 | Band 4.1 domain |
Domain | IPR037837 | Kindlin/fermitin, PH domain |
Domain | IPR040790 | Kindlin-2, N-terminal |
Family | IPR037843 | Kindlin/fermitin |
Homologous_superfamily | IPR011993 | PH-like domain superfamily |
Homologous_superfamily | IPR035963 | FERM superfamily, second domain |
Domain Details Per Protein
Protein | Length | Band 4.1 domain | FERM central domain | FERM superfamily, second domain | Kindlin-2, N-terminal | Kindlin/fermitin | Kindlin/fermitin, PH domain | PH-like domain superfamily | Pleckstrin homology domain |
---|---|---|---|---|---|---|---|---|---|
UniProtKB:A0A2R8RR15
|
688 | ||||||||
UniProtKB:A0A2R8QN11
|
695 | ||||||||
UniProtKB:A0A8M2B5V7
|
677 | ||||||||
UniProtKB:F1Q8X5
|
684 |
Type | Name | Annotation Method | Length (nt) | Analysis |
---|---|---|---|---|
mRNA |
fermt2-201
(1)
|
Havana | 2488 nt | |
mRNA |
fermt2-203
(1)
|
Ensembl | 2430 nt | |
mRNA |
fermt2-204
(1)
|
Ensembl | 2409 nt | |
ncRNA |
fermt2-002
(1)
|
Havana | 840 nt |
Interactions and Pathways
No data available
Plasmids
No data available