ZFIN ID: ZDB-GENE-050419-198
Gene Name: SMAD family member 6b
Gene Symbol: smad6b
Previous Name: si:dkey-288j18.1
Location: Chr: 18 Mapping Details/Browsers
Nomenclature History
GENE EXPRESSION
Directly Submitted Expression Data: 6 figures (13 images) from Thisse et al., 2005 [eu893]
Wild-type Stages, Structures: Segmentation:1-4 somites (10.33h-11.66h) to Hatching:Long-pec (48.0h-60.0h)
  heart rudiment, heart tube, mesoderm, midbrain (all 11) expand
MUTATIONS AND SEQUENCE TARGETING REAGENTS 
Allele Type Mutagen Suppliers
sa10756 Point Mutation ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH smad6b HUMAN ORTHOLOG 
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    aortic valve stenosis Aortic valve disease 2 614823
    GENE ONTOLOGY 
    Ontology GO Term
    Biological Process regulation of transcription, DNA-templated (more)
    Cellular Component cytoplasm (more)
    Molecular Function DNA binding (more)
    GO Terms (all 9)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR001132 (1)
  • InterPro:IPR003619 (1)
  • InterPro:IPR008984 (1)
  • InterPro:IPR013019 (1)
  • InterPro:IPR013790 (1)
  • InterPro:IPR017855 (1)
  • PROSITE:PS51075 (1)
  • PROSITE:PS51076 (1)
  • Pfam:PF03165 (1)
  • Pfam:PF03166 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA smad6b-001 (1) 2113
    GENE PRODUCT DESCRIPTION
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM smad6b No data available
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS 
    smad6bContained in: [BAC] DKEY-288J18 (1) (order this)
    smad6bEncodes: [EST] eu893 (1)
    [cDNA] MGC:162749 (1) (order this)
    SEQUENCE INFORMATION 
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001045051 (1) 2572bp
    Genomic GenBank:CR533570 (1) 167352bp
    Select Tool
    Polypeptide UniProtKB:Q1L8Y3 (1) 486aa
    Sequence Clusters UniGene:23081 (1)
    Sequence Information (all 12)
    OTHER smad6b GENE PAGES 
  • Gene:564395 (1)
  • VEGA:OTTDARG00000013216 (1)
  • Ensembl(GRCz10):ENSDARG00000031763 (1)
  • ORTHOLOGY for smad6b (Chr: 18) 
    Species Symbol Chromosome Accession # Evidence
    Human SMAD6 15
  • Gene:4091
  • OMIM:602931
  • HGNC:6772
  • Amino acid sequence comparison (1)
    Conserved genome location (synteny) (2)
    Mouse Smad6 9
  • MGI:1336883
  • Gene:17130
  • Amino acid sequence comparison (1)
    Conserved genome location (synteny) (1)
    Download Curated Orthology
    CITATIONS (18)