ZFIN ID: ZDB-GENE-050419-198
Gene Name: SMAD family member 6b
Gene Symbol: smad6b
Previous Name: si:dkey-288j18.1
Location: Chr: 18   Details
Nomenclature History
GENE EXPRESSION
Directly Submitted Expression Data: 6 figures (13 images) from Thisse et al., 2005 [eu893]
Wild-type Stages, Structures: Segmentation:1-4 somites (10.33h-11.66h) to Hatching:Long-pec (48.0h-60.0h)
  heart rudiment, heart tube, mesoderm, midbrain (all 11) expand
MUTANTS AND TARGETED KNOCKDOWNS
Alleles: sa10756
PHENOTYPE
Phenotype of Human Orthologue OMIM Phenotype ID
Aortic valve disease 2 614823
GENE ONTOLOGY
Ontology GO Term
Biological Process regulation of transcription, DNA-templated (more)
Cellular Component cytoplasm (more)
Molecular Function DNA binding (more)
GO Terms (all 9)
PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR001132 (1)
  • InterPro:IPR003619 (1)
  • InterPro:IPR008984 (1)
  • InterPro:IPR013019 (1)
  • InterPro:IPR013790 (1)
  • InterPro:IPR017855 (1)
  • PROSITE:PS51075 (1)
  • PROSITE:PS51076 (1)
  • Pfam:PF03165 (1)
  • Pfam:PF03166 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA smad6b-001 (1) 2113
    GENE PRODUCT DESCRIPTION
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM smad6b No data available
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS
    smad6b Contained in: [BAC] DKEY-288J18 (1)
    smad6b Encodes: [EST] eu893 (1)
    [cDNA] MGC:162749 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001045051 (1) 2572 bp
    Genomic GenBank:CR533570 (1) 167352 bp
    Select Tool
    Polypeptide UniProtKB:Q1L8Y3 (1) 486 aa
    Sequence Clusters UniGene:23081 (1)
    Sequence Information (all 11)
    OTHER smad6b GENE PAGES
  • Gene:564395 (1)
  • VEGA:OTTDARG00000013216 (1)
  • Ensembl(Zv9):ENSDARG00000031763 (1)
  • ORTHOLOGY
      Evidence
    Species Symbol Chr (Position) Accession # AA CL
    Zebrafish smad6b 18  
    Human SMAD6 15 (15q22.31)
  • OMIM:602931
  • Gene:4091
  • Mouse Smad6 9 ( 34.40 cM)
  • MGI:1336883
  • Gene:17130
  • Orthology Details
    CITATIONS (17)