ZFIN ID: ZDB-GENE-050419-198
Gene Name: SMAD family member 6b
Gene Symbol: smad6b
Previous Name: si:dkey-288j18.1
Location: Chr: 18   Details
Nomenclature History
GENE EXPRESSION
Directly Submitted Expression Data: 6 figures (13 images) from Thisse et al., 2005 [eu893]
Wild-type Stages, Structures: Segmentation:1-4 somites (10.33h-11.66h) to Hatching:Long-pec (48.0h-60.0h)
  heart rudiment, heart tube, mesoderm, midbrain (all 11) expand
MUTANTS AND TARGETED KNOCKDOWNS
Alleles: sa10756
PHENOTYPE
Phenotype of Human Orthologue OMIM Phenotype ID
Aortic valve disease 2 614823
GENE ONTOLOGY
Ontology GO Term
Biological Process regulation of transcription, DNA-templated (more)
Cellular Component cytoplasm (more)
Molecular Function sequence-specific DNA binding transcription factor activity (more)
GO Terms (all 8)
PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR001132 (1)
  • InterPro:IPR003619 (1)
  • InterPro:IPR008984 (1)
  • InterPro:IPR013019 (1)
  • InterPro:IPR013790 (1)
  • InterPro:IPR017855 (1)
  • PROSITE:PS51075 (1)
  • PROSITE:PS51076 (1)
  • Pfam:PF03165 (1)
  • Pfam:PF03166 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA smad6b-001 (1) 2113
    GENE PRODUCT DESCRIPTION No description available
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM smad6b No data available
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS
    smad6b Contained in: [BAC] DKEY-288J18 (1)
    smad6b Encodes: [EST] eu893 (1)
    [cDNA] MGC:162749 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001045051 (1) 2572 bp
    Genomic GenBank:CR533570 (1) 167352 bp
    Select Tool
    Polypeptide UniProtKB:Q1L8Y3 (1) 486 aa
    Sequence Clusters UniGene:23081 (1)
    Sequence Information (all 11)
    OTHER smad6b GENE PAGES
  • Gene:564395 (1)
  • VEGA:OTTDARG00000013216 (1)
  • Ensembl(Zv9):ENSDARG00000031763 (1)
  • ORTHOLOGY
      Evidence
    Species Symbol Chr (Position) Accession # AA CL
    Zebrafish smad6b 18  
    Human SMAD6 15 (15q22.31)
  • OMIM:602931
  • Gene:4091
  • Mouse Smad6 9 ( 34.40 cM)
  • MGI:1336883
  • Gene:17130
  • Orthology Details
    CITATIONS (17)