ZFIN ID: ZDB-GENE-050419-198
Gene Name: SMAD family member 6b
Gene Symbol: smad6b

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Previous Name: si:dkey-288j18.1

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(Including Attributions)
Location: Chr: 18 Mapping Details/Browsers
Nomenclature History
GENE EXPRESSION
Directly Submitted Expression Data: 6 figures (13 images) from Thisse et al., 2005 [eu893]
Wild-type Stages, Structures: Segmentation:1-4 somites (10.33h-11.66h) to Hatching:Long-pec (48.0h-60.0h)
  heart rudiment, heart tube, mesoderm, midbrain (all 11) expand
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa10756 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH smad6b HUMAN ORTHOLOG
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    aortic valve stenosis Aortic valve disease 2 614823
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process regulation of transcription, DNA-templated (more)
    Cellular Component cytoplasm (more)
    Molecular Function DNA binding (more)
    GO Terms (all 9)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR001132 (1)
  • InterPro:IPR003619 (1)
  • InterPro:IPR008984 (1)
  • InterPro:IPR013019 (1)
  • InterPro:IPR013790 (1)
  • InterPro:IPR017855 (1)
  • PROSITE:PS51075 (1)
  • PROSITE:PS51076 (1)
  • Pfam:PF03165 (1)
  • Pfam:PF03166 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA smad6b-001 (1) 2113
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYSNo data available
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM smad6b No data available
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS
    smad6bContained in: [BAC] DKEY-288J18 (1) (order this)
    smad6bEncodes: [EST] eu893 (1)
    [cDNA] MGC:162749 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001045051 (1) 2572bp
    Genomic GenBank:CR533570 (1) 167352bp
    Select Tool
    Polypeptide UniProtKB:Q1L8Y3 (1) 486aa
    Sequence Clusters UniGene:23081 (1)
    Sequence Information (all 12)
    OTHER smad6b GENE PAGES
  • Gene:564395 (1)
  • VEGA:OTTDARG00000013216 (1)
  • Ensembl(GRCz10):ENSDARG00000031763 (1)
  • ORTHOLOGY for smad6b (Chr: 18)
    Species Symbol Chromosome Accession # Evidence
    Human SMAD6 15
  • Gene:4091
  • OMIM:602931
  • HGNC:6772
  • Amino acid sequence comparison (1)
    Conserved genome location (synteny) (2)
    Mouse Smad6 9
  • MGI:1336883
  • Gene:17130
  • Amino acid sequence comparison (1)
    Conserved genome location (synteny) (1)
    Download Curated Orthology
    CITATIONS (19)