Gene

rrp7a

ID

ZDB-GENE-050417-38

Name

ribosomal RNA processing 7 homolog A

Symbol

rrp7a Nomenclature History

Previous Names

zgc:110084

Type

protein_coding_gene

Location

Chr: 3 Mapping Details/Browsers

Description

Predicted to have RNA binding activity. Predicted to be involved in rRNA processing and ribosomal small subunit assembly. Predicted to localize to CURI complex and UTP-C complex. Orthologous to human RRP7A (ribosomal RNA processing 7 homolog A).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

2 figures from 2 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

MGC:110084 (1 image)

Wild Type Expression Summary

Phenotype

All Phenotype Data: 4 figures from Farooq et al., 2020
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With rrp7a Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
		?Microcephaly 28, primary, autosomal recessive	619453

Associated With rrp7a Via Experimental Models

Human Disease	Fish	Conditions	Citations
primary microcephaly	rrp7a^{sa11429/sa11429} (AB/TL)	standard conditions	Farooq et al., 2020

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR000504	RNA recognition motif domain
Domain	IPR024326	Ribosomal RNA-processing protein 7, C-terminal domain
Domain	IPR034890	Rrp7A, RNA recognition motif
Family	IPR040446	Ribosomal RNA-processing protein 7
Homologous_superfamily	IPR012677	Nucleotide-binding alpha-beta plait domain superfamily
Homologous_superfamily	IPR035979	RNA-binding domain superfamily