Gene

gtf2f2b

ID

ZDB-GENE-050417-374

Name

general transcription factor IIF, polypeptide 2b

Symbol

gtf2f2b Nomenclature History

Previous Names

zgc:110187

Type

protein_coding_gene

Location

Chr: 9 Mapping Details/Browsers

Description

Predicted to have ATP binding activity; DNA binding activity; and DNA helicase activity. Predicted to be involved in positive regulation of transcription elongation from RNA polymerase II promoter and positive regulation of transcription initiation from RNA polymerase II promoter. Predicted to localize to transcription factor TFIIF complex. Orthologous to human GTF2F2 (general transcription factor IIF subunit 2).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

1 figure from Thisse et al., 2004

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Thisse Expression Data

MGC:110187 (1 image)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With gtf2f2b Human Ortholog

No data available

Associated With gtf2f2b Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR040450	TFIIF beta subunit, HTH domain
Domain	IPR040504	TFIIF, beta subunit, N-terminal
Family	IPR003196	Transcription initiation factor IIF, beta subunit
Homologous_superfamily	IPR011039	Transcription Factor IIF, Rap30/Rap74, interaction
Homologous_superfamily	IPR036388	Winged helix-like DNA-binding domain superfamily
Homologous_superfamily	IPR036390	Winged helix DNA-binding domain superfamily