Gene

ccs

ID
ZDB-GENE-050417-322
Name
copper chaperone for superoxide dismutase
Symbol
ccs Nomenclature History
Previous Names
  • zgc:112427
Type
protein_coding_gene
Location
Chr: 7 Mapping Details/Browsers
Description
Predicted to have superoxide dismutase copper chaperone activity. Predicted to be involved in removal of superoxide radicals. Predicted to localize to cytoplasm and nucleus. Human ortholog(s) of this gene implicated in amyotrophic lateral sclerosis. Orthologous to human CCS (copper chaperone for superoxide dismutase).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
1 figure from Thisse et al., 2004
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With ccs Human Ortholog
No data available
Associated With ccs Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Binding_site IPR018152 Superoxide dismutase, copper/zinc, binding site
Domain IPR001424 Superoxide dismutase, copper/zinc binding domain
Domain IPR006121 Heavy metal-associated domain, HMA
Family IPR024134 Superoxide dismutase (Cu/Zn) / superoxide dismutase copper chaperone
Homologous_superfamily IPR036163 Heavy metal-associated domain superfamily
Homologous_superfamily IPR036423 Superoxide dismutase-like, copper/zinc binding domain superfamily
Domain Details Per Protein
Protein Length Heavy metal-associated domain, HMA Heavy metal-associated domain superfamily Superoxide dismutase, copper/zinc binding domain Superoxide dismutase, copper/zinc, binding site Superoxide dismutase (Cu/Zn) / superoxide dismutase copper chaperone Superoxide dismutase-like, copper/zinc binding domain superfamily
UniProtKB:F1QCS3 267
Transcripts
Genome Browsers
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA ccs-201 (1) Ensembl 2,118 nt
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations