Gene
hmgb3b
- ID
- ZDB-GENE-050417-290
- Name
- high mobility group box 3b
- Symbol
- hmgb3b Nomenclature History
- Previous Names
-
- fa19b06
- fj43d02
- wu:fa19b06
- wu:fj43d02
- zgc:112073
- Type
- protein_coding_gene
- Location
- Chr: 21 Mapping Details/Browsers
- Description
- Predicted to have DNA binding activity, bending. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to localize to nuclear chromatin. Is expressed in central nervous system; intermediate cell mass of mesoderm; ovary; and pectoral fin bud. Human ortholog(s) of this gene implicated in syndromic microphthalmia 13. Orthologous to human HMGB3 (high mobility group box 3).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 5 figures from 4 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- IMAGE:6909793 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
---|---|---|---|
?Microphthalmia, syndromic 13 | 300915 |
Domain, Family, and Site Summary
Domain Details Per Protein
Protein | Length | High mobility group box domain | High mobility group box domain superfamily | HMG box A DNA-binding domain, conserved site |
---|---|---|---|---|
UniProtKB:Q567G0
|
198 |
Type | Name | Annotation Method | Length (nt) | Analysis |
---|---|---|---|---|
mRNA |
hmgb3b-201
(1)
|
Havana | 1410 nt | |
mRNA |
hmgb3b-202
(1)
|
Havana | 794 nt | |
mRNA |
hmgb3b-203
(1)
|
Ensembl | 604 nt |
Interactions and Pathways
No data available
Plasmids
No data available