Gene

rhbdl3

ID

ZDB-GENE-050417-2

Name

rhomboid, veinlet-like 3 (Drosophila)

Symbol

rhbdl3 Nomenclature History

Previous Names

si:dkey-10p5.8 (1)
zgc:113283

Type

protein_coding_gene

Location

Chr: 6 Mapping Details/Browsers

Description

Predicted to have serine-type endopeptidase activity. Predicted to be involved in proteolysis. Predicted to localize to integral component of membrane. Is expressed in several structures, including basal plate midbrain region; hatching gland; midbrain neural keel; nervous system; and presumptive diencephalon. Orthologous to human RHBDL3 (rhomboid like 3).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

6 figures from Thisse et al., 2004

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

IMAGE:7159784 (20 images)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With rhbdl3 Human Ortholog

No data available

Associated With rhbdl3 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Binding_site	IPR018247	EF-Hand 1, calcium-binding site
Domain	IPR002048	EF-hand domain
Domain	IPR022764	Peptidase S54, rhomboid domain
Family	IPR017213	Peptidase S54, rhomboid, metazoan
Family	IPR051739	Rhomboid-related Intramembrane Serine Proteases
Homologous_superfamily	IPR011992	EF-hand domain pair
Homologous_superfamily	IPR035952	Rhomboid-like superfamily

Domain Details Per Protein

Protein	Length	EF-Hand 1, calcium-binding site	EF-hand domain	EF-hand domain pair	Peptidase S54, rhomboid domain	Peptidase S54, rhomboid, metazoan	Rhomboid-like superfamily	Rhomboid-related Intramembrane Serine Proteases
UniProtKB:Q2A943 InterPro	407
UniProtKB:A0A8M2BDK9 InterPro	388
UniProtKB:Q566N3 InterPro	306
UniProtKB:A0A8M3BAC5 InterPro	399
UniProtKB:A0A8M9Q644 InterPro	297
UniProtKB:A0A0R4IRL0 InterPro	399

Transcripts

Genome Browsers

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	rhbdl3-201 (1) Ensembl	Ensembl	1,549 nt	Select Tool
mRNA	rhbdl3-202 (1) Ensembl	Ensembl	1,834 nt	Select Tool ZFIN BLAST
mRNA	rhbdl3-203 (1) Ensembl	Ensembl	2,931 nt	Select Tool
mRNA	rhbdl3-204 (1) Ensembl	Ensembl	1,858 nt	Select Tool ZFIN BLAST

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations