Gene

mppe1

ID
ZDB-GENE-050417-195
Name
metallophosphoesterase 1
Symbol
mppe1 Nomenclature History
Previous Names
  • zgc:112219 (1)
Type
protein_coding_gene
Location
Chr: 24 Mapping Details/Browsers
Description
Predicted to have GPI anchor binding activity; GPI-mannose ethanolamine phosphate phosphodiesterase activity; and manganese ion binding activity. Predicted to be involved in GPI anchor biosynthetic process and endoplasmic reticulum to Golgi vesicle-mediated transport. Predicted to localize to cis-Golgi network; endoplasmic reticulum exit site; and endoplasmic reticulum-Golgi intermediate compartment. Orthologous to human MPPE1 (metallophosphoesterase 1).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
1 figure from Thisse et al., 2004
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With mppe1 Human Ortholog
No data available
Associated With mppe1 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR004843 Calcineurin-like phosphoesterase domain, ApaH type
Domain IPR039541 Metallophosphoesterase 1, metallophosphatase domain
Family IPR033308 PGAP5/Cdc1/Ted1
Homologous_superfamily IPR029052 Metallo-dependent phosphatase-like
Domain Details Per Protein
Protein Length Calcineurin-like phosphoesterase domain, ApaH type Metallo-dependent phosphatase-like Metallophosphoesterase 1, metallophosphatase domain PGAP5/Cdc1/Ted1
UniProtKB:A0A8M9P5W1 302
UniProtKB:Q566Y9 381
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations