Gene

mrpl12

ID

ZDB-GENE-050417-187

Name

mitochondrial ribosomal protein L12

Symbol

mrpl12 Nomenclature History

Previous Names

im:6893415
zgc:112445

Type

protein_coding_gene

Location

Chr: 3 Mapping Details/Browsers

Description

Predicted to be a structural constituent of ribosome. Predicted to be involved in mitochondrial transcription. Predicted to localize to mitochondrial large ribosomal subunit. Is expressed in several structures, including alar plate midbrain region; digestive system; optic tectum; optic vesicle; and pectoral fin. Orthologous to human MRPL12 (mitochondrial ribosomal protein L12).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

4 figures from Thisse et al., 2004

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

IMAGE:6893415 (6 images)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With mrpl12 Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
combined oxidative phosphorylation deficiency 45	Alliance	?Combined oxidative phosphorylation deficiency 45	618951

Associated With mrpl12 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR008932	Large ribosomal subunit protein bL12, oligomerization
Domain	IPR013823	Large ribosomal subunit protein bL12, C-terminal
Family	IPR000206	Large ribosomal subunit protein bL12
Homologous_superfamily	IPR014719	Ribosomal protein bL12, C-terminal/adaptor protein ClpS-like
Homologous_superfamily	IPR036235	Large ribosomal subunit protein bL12, oligomerization domain superfamily