Gene

mocos

ID
ZDB-GENE-050327-94
Name
molybdenum cofactor sulfurase
Symbol
mocos Nomenclature History
Previous Names
  • im:7142948
  • zgc:110784 (1)
Type
protein_coding_gene
Location
Chr: 13 Mapping Details/Browsers
Description
Predicted to have Mo-molybdopterin cofactor sulfurase activity. Predicted to be involved in molybdopterin cofactor metabolic process. Human ortholog(s) of this gene implicated in xanthinuria. Is expressed in neural crest. Orthologous to human MOCOS (molybdenum cofactor sulfurase).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
4 figures from Thisse et al., 2004
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With mocos Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
xanthinuria type II Alliance Xanthinuria, type II 603592
Associated With mocos Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR000192 Aminotransferase class V domain
Domain IPR005302 Molybdenum cofactor sulfurase, C-terminal
Domain IPR005303 Molybdenum cofactor sulfurase, middle domain
Family IPR028886 Molybdenum cofactor sulfurase
Homologous_superfamily IPR011037 Pyruvate kinase-like, insert domain superfamily
Homologous_superfamily IPR015421 Pyridoxal phosphate-dependent transferase, major domain
Homologous_superfamily IPR015424 Pyridoxal phosphate-dependent transferase
Domain Details Per Protein
Protein Length Aminotransferase class V domain Molybdenum cofactor sulfurase Molybdenum cofactor sulfurase, C-terminal Molybdenum cofactor sulfurase, middle domain Pyridoxal phosphate-dependent transferase Pyridoxal phosphate-dependent transferase, major domain Pyruvate kinase-like, insert domain superfamily
UniProtKB:A0A8M1N4Y2 851
UniProtKB:A0A8M3B7X2 720
UniProtKB:A2VD33 831
Transcripts
Genome Browsers
No data available
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations