Gene

mtmr1b

ID

ZDB-GENE-050327-48

Name

myotubularin related protein 1b

Symbol

mtmr1b Nomenclature History

Previous Names

wu:fi27f12
zgc:113186

Type

protein_coding_gene

Location

Chr: 21 Mapping Details/Browsers

Description

Predicted to enable phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity and phosphatidylinositol-3-phosphate phosphatase activity. Predicted to be involved in phosphatidylinositol dephosphorylation. Predicted to act upstream of or within dephosphorylation and lipid metabolic process. Predicted to be located in endomembrane system. Predicted to be active in cytoplasm and membrane. Orthologous to human MTMR1 (myotubularin related protein 1).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

1 figure from Thisse et al., 2004

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

MGC:113186 (1 image)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With mtmr1b Human Ortholog

No data available

Associated With mtmr1b Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Active_site	IPR016130	Protein-tyrosine phosphatase, active site
Domain	IPR000387	Tyrosine-specific protein phosphatases domain
Domain	IPR003595	Protein-tyrosine phosphatase, catalytic
Domain	IPR004182	GRAM domain
Domain	IPR010569	Myotubularin-like, phosphatase domain
Family	IPR030564	Myotubularin
Homologous_superfamily	IPR011993	PH-like domain superfamily
Homologous_superfamily	IPR029021	Protein-tyrosine phosphatase-like

Domain Details Per Protein

Protein	Additional Resources	Length	GRAM domain	Myotubularin	Myotubularin-like, phosphatase domain	PH-like domain superfamily	Protein-tyrosine phosphatase, active site	Protein-tyrosine phosphatase, catalytic	Protein-tyrosine phosphatase-like	Tyrosine-specific protein phosphatases domain
UniProtKB:Q58EE0	InterPro	649
UniProtKB:A0A0R4IMW4	InterPro	627

Transcripts

Genome Browsers

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	mtmr1b-201 (1) Ensembl	Ensembl	2,697 nt	Select Tool ZFIN BLAST
mRNA	mtmr1b-203 (1) Ensembl	Ensembl	804 nt	Select Tool ZFIN BLAST
mRNA	mtmr1b-204 (1) Ensembl	Ensembl	964 nt	Select Tool ZFIN BLAST
mRNA	mtmr1b-205 (1) Ensembl	Ensembl	2,688 nt	Select Tool ZFIN BLAST
ncRNA	mtmr1b-004 (1) Ensembl	Ensembl	737 nt	Select Tool ZFIN BLAST

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations