ZFIN ID: ZDB-GENE-050324-2
Gene Name: Wolf-Hirschhorn syndrome candidate 1-like 1
Gene Symbol: whsc1l1
Location: Chr: 10   Details
Nomenclature History
GENE EXPRESSION
All Expression Data: Fig. S6 from Sun et al., 2008
Wild-type Stages, Structures: Cleavage:2-cell (0.75h-1.0h) to Blastula:Sphere (4.0h-4.33h)
  whole organism
MUTANTS AND TARGETED KNOCKDOWNS
Alleles: la017439Tg, la017440Tg, sa11365, sa14276, sa16134 (all 6) expand
Knockdown reagents: MO1-whsc1l1 (1)
PHENOTYPE
Phenotype of Human Orthologue OMIM Phenotype ID
Leukemia, acute myeloid 601626
GENE ONTOLOGY
Ontology GO Term
Biological Process methylation (more)
Cellular Component nucleus (more)
Molecular Function histone-lysine N-methyltransferase activity (more)
GO Terms (all 7)
PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR000313 (1)
  • InterPro:IPR001214 (1)
  • InterPro:IPR001841 (1)
  • InterPro:IPR001965 (1)
  • InterPro:IPR003616 (1)
  • InterPro:IPR006560 (1)
  • InterPro:IPR011011 (1)
  • InterPro:IPR013083 (1)
  • InterPro:IPR019786 (1)
  • InterPro:IPR019787 (1)
  • PROSITE:PS01359 (1)
  • PROSITE:PS50016 (1)
  • PROSITE:PS50280 (1)
  • PROSITE:PS50812 (1)
  • PROSITE:PS50868 (1)
  • PROSITE:PS51215 (1)
  • Pfam:PF00628 (1)
  • Pfam:PF00855 (1)
  • Pfam:PF00856 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA whsc1l1-001 (1) 4396
    GENE PRODUCT DESCRIPTION
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM whsc1l1 No data available
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS
    whsc1l1 Contained in: [BAC] CH73-261P11 (order this), CH211-113D22 (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:XM_005155322 (1) 9562 bp
    Genomic GenBank:BX294119 (1) 167603 bp
    Select Tool
    Polypeptide UniProtKB:F1QV68 (1) 1521 aa
    Sequence Clusters UniGene:95267 (1)
    Sequence Information (all 28)
    OTHER whsc1l1 GENE PAGES
  • Gene:100006350 (1)
  • VEGA:OTTDARG00000030978 (1)
  • Ensembl(Zv9):ENSDARG00000062765 (1)
  • ORTHOLOGY
      Evidence
    Species Symbol Chr (Position) Accession # AA NT CL
    Zebrafish whsc1l1 10  
    Human WHSC1L1 8 (8p11.2)
  • OMIM:607083
  • Gene:54904
  • Mouse Whsc1l1 8 ( 14.17 cM)
  • MGI:2142581
  • Gene:234135
  • Orthology Details
    CITATIONS (19)