Research
General Information
ZIRC
ZFIN ID: ZDB-GENE-050324-2
Gene Name: Wolf-Hirschhorn syndrome candidate 1-like 1
Gene Symbol: whsc1l1
Nomenclature History
GENE EXPRESSION
All Expression Data: Fig. S6 from Sun et al., 2008
Wild-type Stages, Structures: Cleavage:2-cell (0.75h-1.0h) to Blastula:Sphere (4.0h-4.33h)
  whole organism
MUTANTS AND TARGETED KNOCKDOWNS
Alleles: la017439Tg, la017440Tg, sa11365, sa14276, sa16134 (all 6) expand
PHENOTYPE
Phenotype of Human Orthologue OMIM Phenotype ID
Leukemia, acute myeloid 601626
GENE ONTOLOGY
Ontology GO Term
Biological Process methylation (more)
Cellular Component nucleus (more)
Molecular Function histone-lysine N-methyltransferase activity (more)
GO Terms (all 7)
PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR000313 (1)
  • InterPro:IPR001214 (1)
  • InterPro:IPR001841 (1)
  • InterPro:IPR001965 (1)
  • InterPro:IPR003616 (1)
  • InterPro:IPR006560 (1)
  • InterPro:IPR011011 (1)
  • InterPro:IPR013083 (1)
  • InterPro:IPR019786 (1)
  • InterPro:IPR019787 (1)
  • PROSITE:PS01359 (1)
  • PROSITE:PS50016 (1)
  • PROSITE:PS50280 (1)
  • PROSITE:PS50812 (1)
  • PROSITE:PS50868 (1)
  • PROSITE:PS51215 (1)
  • Pfam:PF00628 (1)
  • Pfam:PF00855 (1)
  • Pfam:PF00856 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA whsc1l1-001 (1) 4396
    GENE PRODUCT DESCRIPTION
    ANTIBODIES No data available
    CONSTRUCTS WITH SEQUENCES FROM whsc1l1 No data available
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS
    whsc1l1 Contained in: [BAC] CH73-261P11 (order this), CH211-113D22 (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:XM_005155322 (1) 6718 bp
    Genomic GenBank:BX294119 (1) 167603 bp
    Select Tool
    Polypeptide UniProtKB:F1QV68 (1) 1521 aa
    Sequence Clusters UniGene:95267 (1)
    Sequence Information (all 28)
    OTHER whsc1l1 GENE PAGES
  • Gene:100006350 (1)
  • VEGA:OTTDARG00000030978 (1)
  • Ensembl(Zv9):ENSDARG00000062765 (1)
  • MAPPING INFORMATION
    Chr: 10 Details
    ORTHOLOGY
      Evidence
    Species Symbol Chromosome (Position) Accession # AA NT CL
    Zebrafish whsc1l1 10  
    Human WHSC1L1 8 (8p11.2)
  • OMIM:607083
  • Gene:54904
  • Mouse Whsc1l1 8 ( 14.17 cM)
  • MGI:2142581
  • Gene:234135
  • CITATIONS (18)