Gene
ghrhra
- ID
- ZDB-GENE-050315-2
- Name
- growth hormone releasing hormone receptor a
- Symbol
- ghrhra Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 2 Mapping Details/Browsers
- Description
- Exhibits growth hormone-releasing hormone receptor activity. Involved in adenylate cyclase-modulating G protein-coupled receptor signaling pathway. Predicted to localize to integral component of membrane. Human ortholog(s) of this gene implicated in isolated growth hormone deficiency. Is expressed in several structures, including eye; gill; gut; heart; and pleuroperitoneal region. Orthologous to human GHRHR (growth hormone releasing hormone receptor).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 3 figures from 3 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
---|---|---|---|
isolated growth hormone deficiency type IB | Alliance | Growth hormone deficiency, isolated, type IV | 618157 |
Domain, Family, and Site Summary
Type | InterPro ID | Name |
---|---|---|
Conserved_site | IPR017983 | GPCR, family 2, secretin-like, conserved site |
Domain | IPR001879 | GPCR, family 2, extracellular hormone receptor domain |
Domain | IPR017981 | GPCR, family 2-like, 7TM |
Family | IPR000832 | GPCR, family 2, secretin-like |
Family | IPR050332 | G-protein coupled receptor 2 |
Homologous_superfamily | IPR036445 | GPCR family 2, extracellular hormone receptor domain superfamily |
Domain Details Per Protein
Protein | Length | GPCR, family 2, extracellular hormone receptor domain | GPCR family 2, extracellular hormone receptor domain superfamily | GPCR, family 2-like, 7TM | GPCR, family 2, secretin-like | GPCR, family 2, secretin-like, conserved site | G-protein coupled receptor 2 |
---|---|---|---|---|---|---|---|
UniProtKB:B4XV21
|
432 |
Type | Name | Annotation Method | Length (nt) | Analysis |
---|---|---|---|---|
mRNA |
ghrhra-201
(1)
|
Havana | 1742 nt |
Interactions and Pathways
No data available
Plasmids
No data available