Gene
xpo1a
- ID
- ZDB-GENE-050309-201
- Name
- exportin 1 (CRM1 homolog, yeast) a
- Symbol
- xpo1a Nomenclature History
- Previous Names
-
- im:7151655
- Type
- protein_coding_gene
- Location
- Chr: 1 Mapping Details/Browsers
- Description
- Predicted to enable nuclear export signal receptor activity. Acts upstream of or within brain development. Predicted to be active in cytoplasm and nucleus. Human ortholog(s) of this gene implicated in colorectal cancer; gastric adenocarcinoma; hepatocellular carcinoma; and lung non-small cell carcinoma. Orthologous to human XPO1 (exportin 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Thisse et al., 2004
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- IMAGE:7151655 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- 3 figures from Bagheri et al., 2016
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR001494 | Importin-beta, N-terminal domain |
| Domain | IPR013598 | Exportin-1/Importin-beta-like |
| Domain | IPR014877 | Exportin-1, C-terminal |
| Family | IPR045065 | Exportin-1/5 |
| Homologous_superfamily | IPR011989 | Armadillo-like helical |
| Homologous_superfamily | IPR016024 | Armadillo-type fold |
| Repeat | IPR040485 | Exportin-1, repeat 3 |
| Repeat | IPR041123 | Chromosome region maintenance repeat |
| Repeat | IPR041235 | Exportin-1, repeat 2 |
Domain Details Per Protein
| Protein | Length | Armadillo-like helical | Armadillo-type fold | Chromosome region maintenance repeat | Exportin-1/5 | Exportin-1, C-terminal | Exportin-1/Importin-beta-like | Exportin-1, repeat 2 | Exportin-1, repeat 3 | Importin-beta, N-terminal domain |
|---|---|---|---|---|---|---|---|---|---|---|
|
UniProtKB:E7F0E8
|
1071 |
Interactions and Pathways
No data available
Plasmids
No data available