Gene
rbpjl
- ID
- ZDB-GENE-050307-4
- Name
- recombination signal binding protein for immunoglobulin kappa J region-like
- Symbol
- rbpjl Nomenclature History
- Previous Names
-
- rbpsuhl
- Type
- protein_coding_gene
- Location
- Chr: 6 Mapping Details/Browsers
- Description
- Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in anatomical structure morphogenesis; epithelium development; and nervous system development. Predicted to act upstream of or within regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Orthologous to human RBPJL (recombination signal binding protein for immunoglobulin kappa J region like).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
No data available
No data available
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR015350 | Beta-trefoil DNA-binding domain |
| Domain | IPR015351 | RBP-J/Cbf11/Cbf12, DNA binding |
| Domain | IPR038007 | RBP-Jkappa, IPT domain |
| Family | IPR040159 | Suppressor of hairless-like |
| Homologous_superfamily | IPR008967 | p53-like transcription factor, DNA-binding domain superfamily |
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Domain Details Per Protein
| Protein | Additional Resources | Length | Beta-trefoil DNA-binding domain | Beta-trefoil domain superfamily | Immunoglobulin E-set | Immunoglobulin-like fold | p53-like transcription factor, DNA-binding domain superfamily | RBP-J/Cbf11/Cbf12, DNA binding | RBP-J/Cbf11, DNA binding domain superfamily | RBP-Jkappa, IPT domain | Suppressor of hairless-like |
|---|---|---|---|---|---|---|---|---|---|---|---|
| UniProtKB:A0A8M9QBJ6 | InterPro | 483 |
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Interactions and Pathways
No data available
Plasmids
No data available
No data available
| Relationship | Marker Type | Marker | Accession Numbers | Citations |
|---|---|---|---|---|
| Contained in | BAC | CH211-8I17 |
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| Type | Accession # | Sequence | Length (nt/aa) | Analysis |
|---|---|---|---|---|
| RNA | RefSeq:XM_021477361 (1) | 8319 nt | ||
| Genomic | GenBank:AL954861 (1) | 175026 nt | ||
| Polypeptide | UniProtKB:A0A8M9QBJ6 (1) | 483 aa |
- Elkon, R., Milon, B., Morrison, L., Shah, M., Vijayakumar, S., Racherla, M., Leitch, C.C., Silipino, L., Hadi, S., Weiss-Gayet, M., Barras, E., Schmid, C.D., Ait-Lounis, A., Barnes, A., Song, Y., Eisenman, D.J., Eliyahu, E., Frolenkov, G.I., Strome, S.E., Durand, B., Zaghloul, N.A., Jones, S.M., Reith, W., Hertzano, R. (2015) RFX transcription factors are essential for hearing in mice. Nature communications. 6:8549
- Ko, Y.P., Kobbe, B., Paulsson, M., and Wagener, R. (2005) Zebrafish (Danio rerio) matrilins: shared and divergent characteristics with their mammalian counterparts. The Biochemical journal. 386(Pt 2):367-79
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