Gene

ndufaf1

ID

ZDB-GENE-050306-9

Name

NADH:ubiquinone oxidoreductase complex assembly factor 1

Symbol

ndufaf1 Nomenclature History

Previous Names

fk33c03
wu:fk33c03
zgc:113197 (1)

Type

protein_coding_gene

Location

Chr: 13 Mapping Details/Browsers

Description

Predicted to have unfolded protein binding activity. Predicted to be involved in mitochondrial electron transport, NADH to ubiquinone and mitochondrial respiratory chain complex I assembly. Predicted to localize to mitochondrion. Human ortholog(s) of this gene implicated in mitochondrial complex I deficiency. Orthologous to human NDUFAF1 (NADH:ubiquinone oxidoreductase complex assembly factor 1).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

No data available

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With ndufaf1 Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
nuclear type mitochondrial complex I deficiency 11	Alliance	Mitochondrial complex I deficiency, nuclear type 11	618234

Associated With ndufaf1 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR013857	NADH:ubiquinone oxidoreductase intermediate-associated protein 30
Family	IPR039131	Complex I intermediate-associated protein 30, mitochondrial
Homologous_superfamily	IPR008979	Galactose-binding-like domain superfamily

Domain Details Per Protein

Protein	Length	Complex I intermediate-associated protein 30, mitochondrial	Galactose-binding-like domain superfamily	NADH:ubiquinone oxidoreductase intermediate-associated protein 30
UniProtKB:Q5CZW0 InterPro	304

Transcripts

Genome Browsers

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	ndufaf1-201 (1) Ensembl	Ensembl	1,361 nt	Select Tool ZFIN BLAST
mRNA	ndufaf1-202 (1) Ensembl	Ensembl	846 nt	Select Tool
mRNA	ndufaf1-203 (1) Ensembl	Ensembl	874 nt	Select Tool
mRNA	ndufaf1-204 (1) Ensembl	Ensembl	1,195 nt	Select Tool
mRNA	ndufaf1-205 (1) Ensembl	Ensembl	730 nt	Select Tool
mRNA	ndufaf1-206 (1) Ensembl	Ensembl	1,401 nt	Select Tool
mRNA	ndufaf1-208 (1) Ensembl	Ensembl	444 nt	Select Tool
ncRNA	ndufaf1-007 (1) Ensembl	Ensembl	753 nt	Select Tool

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations