Gene
ifi44a8
- ID
- ZDB-GENE-050302-48
- Name
- interferon induced protein 44a8
- Symbol
- ifi44a8 Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 1 Mapping Details/Browsers
- Description
- Predicted to enable GTP binding activity. Predicted to be involved in immune response. Orthologous to human IFI44 (interferon induced protein 44) and IFI44L (interferon induced protein 44 like).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Rajshekar et al., 2018
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
No data available
No data available
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | GTP binding domain | P-loop containing nucleoside triphosphate hydrolase |
|---|---|---|---|
|
UniProtKB:A0A8M9PWW8
|
292 | ||
|
UniProtKB:A0A8M9PJH7
|
295 | ||
|
UniProtKB:A0A8M1PZX7
|
297 |
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| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
si:dkey-79f11.10-201
(1)
|
Ensembl | 1,215 nt |
1 - 1 of 1
Interactions and Pathways
No data available
Plasmids
No data available
No data available
| Relationship | Marker Type | Marker | Accession Numbers | Citations |
|---|---|---|---|---|
| Contained in | BAC | DKEY-79F11 | ZFIN Curated Data | |
| Encodes | EST | fb66c11 | ||
| Encodes | EST | IMAGE:7041156 |
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| Type | Accession # | Sequence | Length (nt/aa) | Analysis |
|---|---|---|---|---|
| RNA | RefSeq:XM_001345921 (1) | 1201 nt | ||
| Genomic | GenBank:CR855320 (1) | 160757 nt | ||
| Polypeptide | UniProtKB:A0A8M1PZX7 (1) | 297 aa |
No data available
- Levraud, J.P., Jouneau, L., Briolat, V., Laghi, V., Boudinot, P. (2019) IFN-Stimulated Genes in Zebrafish and Humans Define an Ancient Arsenal of Antiviral Immunity. Journal of immunology (Baltimore, Md. : 1950). 203(12):3361-3373
- Rajshekar, S., Yao, J., Arnold, P.K., Payne, S.G., Zhang, Y., Bowman, T.V., Schmitz, R.J., Edwards, J.R., Goll, M. (2018) Pericentromeric hypomethylation elicits an interferon response in an animal model of ICF syndrome. eLIFE. 7:
- Elkon, R., Milon, B., Morrison, L., Shah, M., Vijayakumar, S., Racherla, M., Leitch, C.C., Silipino, L., Hadi, S., Weiss-Gayet, M., Barras, E., Schmid, C.D., Ait-Lounis, A., Barnes, A., Song, Y., Eisenman, D.J., Eliyahu, E., Frolenkov, G.I., Strome, S.E., Durand, B., Zaghloul, N.A., Jones, S.M., Reith, W., Hertzano, R. (2015) RFX transcription factors are essential for hearing in mice. Nature communications. 6:8549
- Briolat, V., Jouneau, L., Carvalho, R., Palha, N., Langevin, C., Herbomel, P., Schwartz, O., Spaink, H.P., Levraud, J.P., Boudinot, P. (2014) Contrasted Innate Responses to Two Viruses in Zebrafish: Insights into the Ancestral Repertoire of Vertebrate IFN-Stimulated Genes. Journal of immunology (Baltimore, Md. : 1950). 192:4328-41
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