Gene

pmpcb

ID
ZDB-GENE-050220-10
Name
peptidase, mitochondrial processing subunit beta
Symbol
pmpcb Nomenclature History
Previous Names
  • zgc:110738 (1)
Type
protein_coding_gene
Location
Chr: 4 Mapping Details/Browsers
Description
Predicted to contribute to endopeptidase activity. Predicted to be involved in protein processing involved in protein targeting to mitochondrion. Predicted to localize to mitochondrial inner membrane and mitochondrial processing peptidase complex. Human ortholog(s) of this gene implicated in multiple mitochondrial dysfunctions syndrome 6. Orthologous to human PMPCB (peptidase, mitochondrial processing subunit beta).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
1 figure from Thisse et al., 2004
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With pmpcb Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
multiple mitochondrial dysfunctions syndrome 6 Alliance Multiple mitochondrial dysfunctions syndrome 6 617954
Associated With pmpcb Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Binding_site IPR001431 Peptidase M16, zinc-binding site
Domain IPR007863 Peptidase M16, C-terminal
Domain IPR011765 Peptidase M16, N-terminal
Homologous_superfamily IPR011249 Metalloenzyme, LuxS/M16 peptidase-like
Domain Details Per Protein
Protein Length Metalloenzyme, LuxS/M16 peptidase-like Peptidase M16, C-terminal Peptidase M16, N-terminal Peptidase M16, zinc-binding site
UniProtKB:Q5EB15 470
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations