Research
General Information
ZIRC
ZFIN ID: ZDB-GENE-050208-585
Gene Name: protein tyrosine phosphatase, receptor type, C
Gene Symbol: ptprc
Previous Names: cd45 (1), si:dkeyp-47c5.1
Location: Chr: 22   Details
Nomenclature History
GENE EXPRESSION
All Expression Data: 7 figures from 4 publications
Wild-type Stages, Structures: Pharyngula:Prim-5 (24.0h-30.0h) to Larval:Protruding-mouth (72.0h-96.0h, 3.5mm)
  blood island, common myeloid progenitor, hematopoietic stem cell, intermediate cell mass of mesoderm (all 5) expand
Curated Microarray Expression: GEO (1)
MUTANTS AND TARGETED KNOCKDOWNS
Alleles: sa9795
PHENOTYPE
Phenotype of Human Orthologue OMIM Phenotype ID
Severe combined immunodeficiency, T cell-negative, B-cell/natural killer-cell positive 608971
{Hepatitic C virus, susceptibility to} 609532
GENE ONTOLOGY
Ontology GO Term
Biological Process dephosphorylation (more)
Molecular Function hydrolase activity (more)
GO Terms (all 6)
PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR000242 (1)
  • InterPro:IPR000387 (1)
  • InterPro:IPR003961 (1)
  • InterPro:IPR013783 (1)
  • InterPro:IPR016130 (1)
  • InterPro:IPR029021 (1)
  • PROSITE:PS00383 (1)
  • PROSITE:PS50055 (1)
  • PROSITE:PS50056 (1)
  • PROSITE:PS50853 (1)
  • Pfam:PF00102 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA ptprc-001 (1) 3226
    ptprc-002 (1) 771
    GENE PRODUCT DESCRIPTION
    ANTIBODIES No data available
    CONSTRUCTS WITH SEQUENCES FROM ptprc
    Tg(ptprc:DsRed)
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS
    ptprc Contained in: [BAC] DKEYP-47C5 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:XM_005161749 (1) 5127 bp
    Genomic GenBank:BX469928 (1) 141594 bp
    Select Tool
    Polypeptide UniProtKB:F1R8P8 (1) 1321 aa
    Sequence Clusters UniGene:83560 (1)
    Sequence Information (all 21)
    OTHER ptprc GENE PAGES
  • Gene:559154 (1)
  • VEGA:OTTDARG00000010303 (1)
  • Ensembl(Zv9):ENSDARG00000071437 (1)
  • ORTHOLOGY
      Evidence
    Species Symbol Chr (Position) Accession # AA CL
    Zebrafish ptprc 22  
    Human PTPRC 1 (1q31-q32)
  • OMIM:151460
  • Gene:5788
  • Mouse Ptprc 1 ( 60.73 cM)
  • MGI:97810
  • Gene:19264
  • Orthology Details
    CITATIONS (20)