ZFIN ID: ZDB-GENE-050208-585
Gene Name: protein tyrosine phosphatase, receptor type, C
Gene Symbol: ptprc
Previous Names: cd45 (1), si:dkeyp-47c5.1
Location: Chr: 22 Details
Nomenclature History
GENE EXPRESSION
All Expression Data: 7 figures from 4 publications
Wild-type Stages, Structures: Pharyngula:Prim-5 (24.0h-30.0h) to Larval:Protruding-mouth (72.0h-96.0h, 3.5mm)
  blood island, common myeloid progenitor, hematopoietic stem cell, intermediate cell mass of mesoderm (all 5) expand
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Mutagen Suppliers
sa9795 Point Mutation ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • European Zebrafish Resource Center (EZRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH ptprc HUMAN ORTHOLOG
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    Severe combined immunodeficiency, T cell-negative, B-cell/natural killer-cell positive 608971
    {Hepatitic C virus, susceptibility to} 609532
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process dephosphorylation (more)
    Cellular Component integral component of membrane (more)
    Molecular Function hydrolase activity (more)
    GO Terms (all 8)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR000242 (1)
  • InterPro:IPR000387 (1)
  • InterPro:IPR003961 (1)
  • InterPro:IPR013783 (1)
  • InterPro:IPR016130 (1)
  • InterPro:IPR029021 (1)
  • PROSITE:PS00383 (1)
  • PROSITE:PS50055 (1)
  • PROSITE:PS50056 (1)
  • Pfam:PF00102 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA ptprc-001 (1) 3226
    ptprc-002 (1) 771
    GENE PRODUCT DESCRIPTION
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM ptprc
    Tg(ptprc:DsRed)
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS
    ptprcContained in: [BAC] DKEYP-47C5 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:XM_009296372 (1) 4919bp
    Genomic GenBank:BX469928 (1) 141594bp
    Select Tool
    Polypeptide UniProtKB:F1R8P8 (1) 1321aa
    Sequence Clusters UniGene:125091 (1)
    Sequence Information (all 20)
    OTHER ptprc GENE PAGES
  • Gene:559154 (1)
  • VEGA:OTTDARG00000010303 (1)
  • Ensembl(GRCz10):ENSDARG00000071437 (1)
  • ORTHOLOGY for ptprc (Chr: 22)
    Species Symbol Chromosome Accession # Evidence
    Human PTPRC 1
  • Gene:5788
  • OMIM:151460
  • HGNC:9666
  • Amino acid sequence comparison (2)
    Conserved genome location (synteny) (1)
    Mouse Ptprc 1
  • MGI:97810
  • Gene:19264
  • Amino acid sequence comparison (1)
    Conserved genome location (synteny) (1)
    Download Curated Orthology
    CITATIONS (20)