Gene

cnnm2a

ID
ZDB-GENE-050208-36
Name
cyclin and CBS domain divalent metal cation transport mediator 2a
Symbol
cnnm2a Nomenclature History
Previous Names
  • im:7136247
  • si:ch211-67n3.4
Type
protein_coding_gene
Location
Chr: 13 Mapping Details/Browsers
Description
Predicted to have magnesium ion transmembrane transporter activity. Involved in brain development and magnesium ion homeostasis. Predicted to localize to plasma membrane. Human ortholog(s) of this gene implicated in renal hypomagnesemia 6. Is expressed in several structures, including brain; digestive system; midbrain hindbrain boundary neural keel; pleuroperitoneal region; and scale. Orthologous to human CNNM2 (cyclin and CBS domain divalent metal cation transport mediator 2).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
12 figures from 5 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
12 figures from 3 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With cnnm2a Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
renal hypomagnesemia 6 Alliance Hypomagnesemia 6, renal 613882
Hypomagnesemia, seizures, and impaired intellectual development 1 616418
Associated With cnnm2a Via Experimental Models
Human Disease Fish Conditions Citations
schizophrenia cnnm2aa357/a357 standard conditions Thyme et al., 2019
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR000644 CBS domain
Domain IPR002550 CNNM, transmembrane domain
Domain IPR044751 Ion transporter-like, CBS domain
Family IPR045095 Ancient conserved domain protein family
Homologous_superfamily IPR046342 CBS domain superfamily
Domain Details Per Protein
Protein Length Ancient conserved domain protein family CBS domain CBS domain superfamily CNNM, transmembrane domain Ion transporter-like, CBS domain
UniProtKB:A2ATX7 811
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations