Gene
slx4
- ID
- ZDB-GENE-050208-359
- Name
- SLX4 structure-specific endonuclease subunit homolog (S. cerevisiae)
- Symbol
- slx4 Nomenclature History
- Previous Names
-
- btbd12
- fancp (1)
- si:dkey-44g23.4
- Type
- protein_coding_gene
- Location
- Chr: 22 Mapping Details/Browsers
- Description
- Predicted to enable metal ion binding activity. Acts upstream of or within gallbladder development and hepatic duct development. Predicted to be located in membrane and nucleus. Predicted to be part of Slx1-Slx4 complex. Human ortholog(s) of this gene implicated in Fanconi anemia complementation group P. Orthologous to human SLX4 (SLX4 structure-specific endonuclease subunit).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Fanconi anemia complementation group P | Alliance | Fanconi anemia, complementation group P | 613951 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | BTB/POZ domain | SKP1/BTB/POZ domain superfamily | Structure-specific endonuclease subunit Slx4 | Zinc finger C2H2-type |
|---|---|---|---|---|---|
|
UniProtKB:F1QPU2
|
1719 | ||||
|
UniProtKB:A0A8M1RN23
|
1720 |
Interactions and Pathways
No data available
Plasmids
No data available
- Comparative Orthology
- Alliance