Gene
ift80
- ID
- ZDB-GENE-041212-50
- Name
- intraflagellar transport 80 homolog (Chlamydomonas)
- Symbol
- ift80 Nomenclature History
- Previous Names
-
- wu:fj11a06
- zgc:101763
- Type
- protein_coding_gene
- Location
- Chr: 15 Mapping Details/Browsers
- Description
- Acts upstream of or within several processes, including cilium assembly; convergent extension; and retina morphogenesis in camera-type eye. Predicted to be located in motile cilium. Predicted to be part of intraciliary transport particle B. Predicted to be active in centrosome and cilium. Is expressed in several structures, including eye; notochord; pectoral fin; pectoral fin bud; and pronephric duct. Used to study asphyxiating thoracic dystrophy; asphyxiating thoracic dystrophy 2; and ciliopathy. Human ortholog(s) of this gene implicated in asphyxiating thoracic dystrophy 2. Orthologous to human IFT80 (intraflagellar transport 80).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 2 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:101763 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- 11 figures from 3 publications
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| asphyxiating thoracic dystrophy 2 | Alliance | Short-rib thoracic dysplasia 2 with or without polydactyly | 611263 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | WD40 repeat | WD40-repeat-containing domain superfamily | WD40/YVTN repeat-like-containing domain superfamily |
|---|---|---|---|---|
|
UniProtKB:A0A8M2BKN3
|
779 | |||
|
UniProtKB:Q5PRA9
|
777 |
Interactions and Pathways
No data available
Plasmids
No data available