Gene
tafa5a
- ID
- ZDB-GENE-041210-344
- Name
- TAFA chemokine like family member 5a
- Symbol
- tafa5a Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 4 Mapping Details/Browsers
- Description
- Predicted to enable G protein-coupled receptor binding activity and receptor ligand activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in membrane. Predicted to be active in extracellular space. Is expressed in brain. Orthologous to human TAFA5 (TAFA chemokine like family member 5).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Choi et al., 2018
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
| Allele | Type | Localization | Consequence | Mutagen | Supplier |
|---|---|---|---|---|---|
| la015398Tg | Transgenic insertion | Unknown | Unknown | DNA | |
| la024545Tg | Transgenic insertion | Unknown | Unknown | DNA | |
| la029006Tg | Transgenic insertion | Unknown | Unknown | DNA |
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No data available
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Chemokine-like protein TAFA | Chemokine-like protein TAFA-5 |
|---|---|---|---|
|
UniProtKB:A0A8M2BGH3
|
132 | ||
|
UniProtKB:E9QB79
|
111 | ||
|
UniProtKB:H0WEJ8
|
132 | ||
|
UniProtKB:A0A2R8QIB8
|
133 | ||
|
UniProtKB:A2BIC8
|
131 |
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| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
fam19a5a-202
(1)
|
Ensembl | 659 nt | ||
| mRNA |
fam19a5a-203
(1)
|
Ensembl | 962 nt | ||
| mRNA |
fam19a5a-204
(1)
|
Ensembl | 399 nt | ||
| mRNA |
tafa5a-201
(1)
|
Ensembl | 1,736 nt | ||
| mRNA |
tafa5a-205
(1)
|
Ensembl | 418 nt |
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Interactions and Pathways
No data available
Plasmids
No data available
No data available
| Relationship | Marker Type | Marker | Accession Numbers | Citations |
|---|---|---|---|---|
| Contained in | BAC | CH73-149G16 | ZFIN Curated Data | |
| Contained in | BAC | CH211-203N20 | ZFIN Curated Data | |
| Contained in | BAC | DKEY-27F18 | ZFIN Curated Data | |
| Contained in | BAC | DKEY-164M14 | ZFIN Curated Data | |
| Contained in | BAC | DKEY-200M9 | ZFIN Curated Data |
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| Type | Accession # | Sequence | Length (nt/aa) | Analysis |
|---|---|---|---|---|
| RNA | RefSeq:NM_001430368 (1) | 2598 nt | ||
| Genomic | RefSeq:NW_018394558 (1) | |||
| Polypeptide | UniProtKB:A0A2R8QIB8 (1) | 133 aa |
- Jeong, I., Yun, S., Shahapal, A., Cho, E.B., Hwang, S.W., Seong, J.Y., Park, H.C. (2021) FAM19A5l Affects Mustard Oil-Induced Peripheral Nociception in Zebrafish. Molecular neurobiology. 58(9):4770-4785
- Choi, J.H., Jeong, Y.M., Kim, S., Lee, B., Ariyasiri, K., Kim, H.T., Jung, S.H., Hwang, K.S., Choi, T.I., Park, C.O., Huh, W.K., Carl, M., Rosenfeld, J.A., Raskin, S., Ma, A., Gecz, J., Kim, H.G., Kim, J.S., Shin, H.C., Park, D.S., Gerlai, R., Jamieson, B.B., Kim, J.S., Iremonger, K.J., Lee, S.H., Shin, H.S., Kim, C.H. (2018) Targeted knockout of a chemokine-like gene increases anxiety and fear responses. Proceedings of the National Academy of Sciences of the United States of America. 115(5):E1041-E1050
- Varshney, G.K., Lu, J., Gildea, D., Huang, H., Pei, W., Yang, Z., Huang, S.C., Schoenfeld, D.S., Pho, N., Casero, D., Hirase, T., Mosbrook-Davis, D.M., Zhang, S., Jao, L.E., Zhang, B., Woods, I.G., Zimmerman, S., Schier, A.F., Wolfsberg, T., Pellegrini, M., Burgess, S.M., and Lin, S. (2013) A large-scale zebrafish gene knockout resource for the genome-wide study of gene function. Genome research. 23(4):727-735
- Wang, D., Jao, L.E., Zheng, N., Dolan, K., Ivey, J., Zonies, S., Wu, X., Wu, K., Yang, H., Meng, Q., Zhu, Z., Zhang, B., Lin, S., and Burgess, S.M. (2007) Efficient genome-wide mutagenesis of zebrafish genes by retroviral insertions. Proceedings of the National Academy of Sciences of the United States of America. 104(30):12428-12433
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