Gene

stab2

ID

ZDB-GENE-041210-336

Name

stabilin 2

Symbol

stab2 Nomenclature History

Previous Names

si:dkey-207j16.6

Type

protein_coding_gene

Location

Chr: 4 Mapping Details/Browsers

Description

Enables scavenger receptor activity. Acts upstream of or within several processes, including cholesterol homeostasis; low-density lipoprotein particle clearance; and oxidised low-density lipoprotein particle clearance. Predicted to be located in membrane. Is expressed in several structures, including angioblastic mesenchymal cell; caudal hematopoietic tissue; lateral plate mesoderm; vascular cord; and vasculature. Orthologous to human STAB2 (stabilin 2).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

14 figures from 12 publications

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: 9 figures from 5 publications
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With stab2 Human Ortholog

No data available

Associated With stab2 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR000538	Link domain
Domain	IPR000742	EGF-like domain
Domain	IPR000782	FAS1 domain
Domain	IPR001881	EGF-like calcium-binding domain
Domain	IPR002049	Laminin-type EGF domain
Domain	IPR024731	EGF domain
Homologous_superfamily	IPR009030	Growth factor receptor cysteine-rich domain superfamily
Homologous_superfamily	IPR016186	C-type lectin-like/link domain superfamily
Homologous_superfamily	IPR016187	C-type lectin fold
Homologous_superfamily	IPR036378	FAS1 domain superfamily

Domain Details Per Protein

Protein	Length	C-type lectin fold	C-type lectin-like/link domain superfamily	EGF domain	EGF-like calcium-binding domain	EGF-like domain	FAS1 domain	FAS1 domain superfamily	Growth factor receptor cysteine-rich domain superfamily	Laminin-type EGF domain	Link domain
UniProtKB:C6GHV6 InterPro	2508
UniProtKB:A0A8M9PUI5 InterPro	1703
UniProtKB:F6P8Y7 InterPro	2543

Transcripts

Genome Browsers

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	stab2-201 (1) Ensembl	Ensembl	7,527 nt	Select Tool ZFIN BLAST
mRNA	stab2-202 (1) Ensembl	Ensembl	8,055 nt	Select Tool ZFIN BLAST
mRNA	stab2-204 (1) Ensembl	Ensembl	2,159 nt	Select Tool ZFIN BLAST
ncRNA	stab2-003 (1) Ensembl	Ensembl	301 nt	Select Tool ZFIN BLAST

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations