Gene

sptlc3

ID

ZDB-GENE-041210-281

Name

serine palmitoyltransferase, long chain base subunit 3

Symbol

sptlc3 Nomenclature History

Previous Names

si:dkey-246k9.1 (1)

Type

protein_coding_gene

Location

Chr: 13 Mapping Details/Browsers

Description

Predicted to have catalytic activity and pyridoxal phosphate binding activity. Predicted to be involved in biosynthetic process. Predicted to localize to integral component of membrane. Is expressed in EVL; gut; periderm; and pronephric duct. Orthologous to human SPTLC3 (serine palmitoyltransferase long chain base subunit 3).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

6 figures from Thisse et al., 2004

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

IMAGE:7155977 (6 images)

Wild Type Expression Summary

Phenotype

All Phenotype Data: 1 Figure from Gonzaga-Jauregui et al., 2015
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With sptlc3 Human Ortholog

No data available

Associated With sptlc3 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR004839	Aminotransferase, class I/classII, large domain
Family	IPR050087	8-amino-7-oxononanoate synthase class-II
Homologous_superfamily	IPR015421	Pyridoxal phosphate-dependent transferase, major domain
Homologous_superfamily	IPR015422	Pyridoxal phosphate-dependent transferase, small domain
Homologous_superfamily	IPR015424	Pyridoxal phosphate-dependent transferase

Domain Details Per Protein

Protein	Length	8-amino-7-oxononanoate synthase class-II	Aminotransferase, class I/classII, large domain	Pyridoxal phosphate-dependent transferase	Pyridoxal phosphate-dependent transferase, major domain	Pyridoxal phosphate-dependent transferase, small domain
UniProtKB:A0A8M9Q9N3 InterPro	553
UniProtKB:Q6DC52 InterPro	553
UniProtKB:A0A8M9QND3 InterPro	282

Transcripts

Genome Browsers

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	sptlc3-201 (1) Ensembl	Ensembl	2,101 nt	Select Tool ZFIN BLAST
mRNA	sptlc3-202 (1) Ensembl	Ensembl	1,020 nt	Select Tool ZFIN BLAST
mRNA	sptlc3-203 (1) Ensembl	Ensembl	2,510 nt	Select Tool ZFIN BLAST

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations