Gene
net1
- ID
- ZDB-GENE-041121-18
- Name
- neuroepithelial cell transforming 1
- Symbol
- net1 Nomenclature History
- Previous Names
-
- wu:fb13g03
- wu:fb25c11
- zgc:92121
- Type
- protein_coding_gene
- Location
- Chr: 4 Mapping Details/Browsers
- Description
- Predicted to have Rho guanyl-nucleotide exchange factor activity. Involved in several processes, including dorsal/ventral axis specification; mesendoderm development; and regulation of nodal signaling pathway. Is expressed in axial mesoderm; margin; and shield. Orthologous to human NET1 (neuroepithelial cell transforming 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 5 figures from 4 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR001331 | Guanine-nucleotide dissociation stimulator, CDC24, conserved site |
| Domain | IPR000219 | Dbl homology (DH) domain |
| Domain | IPR001849 | Pleckstrin homology domain |
| Family | IPR051480 | Endocytic & GEF Adapter |
| Homologous_superfamily | IPR011993 | PH-like domain superfamily |
| Homologous_superfamily | IPR035899 | Dbl homology (DH) domain superfamily |
Domain Details Per Protein
| Protein | Length | Dbl homology (DH) domain | Dbl homology (DH) domain superfamily | Endocytic & GEF Adapter | Guanine-nucleotide dissociation stimulator, CDC24, conserved site | PH-like domain superfamily | Pleckstrin homology domain |
|---|---|---|---|---|---|---|---|
|
UniProtKB:Q5RKM4
|
551 | ||||||
|
UniProtKB:Q5RHT9
|
580 | ||||||
|
UniProtKB:A0A8M9Q5V8
|
605 |
Interactions and Pathways
No data available
Plasmids
No data available