Gene
eif4eb
- ID
- ZDB-GENE-041121-14
- Name
- eukaryotic translation initiation factor 4eb
- Symbol
- eif4eb Nomenclature History
- Previous Names
-
- zgc:101581 (1)
- Type
- protein_coding_gene
- Location
- Chr: 13 Mapping Details/Browsers
- Description
- Predicted to enable RNA 7-methylguanosine cap binding activity and translation initiation factor activity. Predicted to act upstream of or within translational initiation. Predicted to be located in cytoplasm. Predicted to be part of eukaryotic translation initiation factor 4F complex. Is expressed in several structures, including hatching gland; head; optic tectum; polster; and solid lens vesicle. Human ortholog(s) of this gene implicated in autistic disorder. Orthologous to human EIF4E (eukaryotic translation initiation factor 4E).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 6 figures from Thisse et al., 2004
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:101581 (12 images)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| {Autism, susceptibility to, 19} | 615091 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Eukaryotic translation initiation factor 4E (eIF-4E), conserved site | Translation Initiation factor eIF- 4e | Translation Initiation factor eIF- 4e-like |
|---|---|---|---|---|
|
UniProtKB:Q5RKQ5
|
216 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
eif4eb-201
(1)
|
Ensembl | 1,563 nt |
Interactions and Pathways
No data available
Plasmids
No data available