Gene
haao
- ID
- ZDB-GENE-041114-89
- Name
- 3-hydroxyanthranilate 3,4-dioxygenase
- Symbol
- haao Nomenclature History
- Previous Names
-
- zgc:103585
- Type
- protein_coding_gene
- Location
- Chr: 13 Mapping Details/Browsers
- Description
- Predicted to have 3-hydroxyanthranilate 3,4-dioxygenase activity and ferrous iron binding activity. Predicted to be involved in 'de novo' NAD biosynthetic process from tryptophan and quinolinate biosynthetic process. Predicted to localize to cytoplasm. Is expressed in intestinal bulb and liver. Orthologous to human HAAO (3-hydroxyanthranilate 3,4-dioxygenase).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 7 figures from Thisse et al., 2004
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:103585 (5 images)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Vertebral, cardiac, renal, and limb defects syndrome 1 | 617660 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | 3-hydroxyanthranilate 3, 4-dioxygenase, metazoan | 3-hydroxyanthranilic acid dioxygenase | RmlC-like cupin domain superfamily | RmlC-like jelly roll fold |
|---|---|---|---|---|---|
|
UniProtKB:B2GQ93
|
287 | ||||
|
UniProtKB:F1QYC7
|
287 | ||||
|
UniProtKB:Q5U3F8
|
287 |
Interactions and Pathways
No data available
Plasmids
No data available