Gene
haao
- ID
- ZDB-GENE-041114-89
- Name
- 3-hydroxyanthranilate 3,4-dioxygenase
- Symbol
- haao Nomenclature History
- Previous Names
-
- zgc:103585
- Type
- protein_coding_gene
- Location
- Chr: 13 Mapping Details/Browsers
- Description
- Predicted to enable 3-hydroxyanthranilate 3,4-dioxygenase activity and ferrous iron binding activity. Predicted to be involved in 'de novo' NAD+ biosynthetic process from L-tryptophan and quinolinate biosynthetic process. Predicted to be located in cytosol. Predicted to be active in cytoplasm. Is expressed in intestinal bulb and liver. Orthologous to human HAAO (3-hydroxyanthranilate 3,4-dioxygenase).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 7 figures from Thisse et al., 2004
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:103585 (5 images)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Vertebral, cardiac, renal, and limb defects syndrome 1 | 617660 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | 3-hydroxyanthranilate 3, 4-dioxygenase, metazoan | 3-hydroxyanthranilic acid dioxygenase | RmlC-like cupin domain superfamily | RmlC-like jelly roll fold |
|---|---|---|---|---|---|---|
| UniProtKB:B2GQ93 | InterPro | 287 | ||||
| UniProtKB:F1QYC7 | InterPro | 287 | ||||
| UniProtKB:Q5U3F8 | InterPro | 287 |
Interactions and Pathways
No data available
Plasmids
No data available