Gene

spire2

ID
ZDB-GENE-041114-29
Name
spire-type actin nucleation factor 2
Symbol
spire2 Nomenclature History
Previous Names
  • zgc:103506 (1)
Type
protein_coding_gene
Location
Chr: 25 Mapping Details/Browsers
Description
Predicted to have actin binding activity. Predicted to be involved in formin-nucleated actin cable assembly and positive regulation of double-strand break repair. Predicted to localize to several cellular components, including cytoplasmic vesicle membrane; cytoskeleton; and cytosol. Orthologous to human SPIRE2 (spire type actin nucleation factor 2).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
1 figure from Thisse et al., 2004
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With spire2 Human Ortholog
No data available
Associated With spire2 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR003124 WH2 domain
Domain IPR011019 KIND domain
Family IPR029901 Protein Spire
Homologous_superfamily IPR011011 Zinc finger, FYVE/PHD-type
Domain Details Per Protein
Protein Length KIND domain Protein Spire WH2 domain Zinc finger, FYVE/PHD-type
UniProtKB:E7EZ28 730
UniProtKB:Q5U3H9 606
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations