Gene

neil3

ID

ZDB-GENE-041114-18

Name

nei-like DNA glycosylase 3

Symbol

neil3 Nomenclature History

Previous Names

zgc:103553 (1)

Type

protein_coding_gene

Location

Chr: 14 Mapping Details/Browsers

Description

Predicted to enable DNA N-glycosylase activity and DNA-(apurinic or apyrimidinic site) endonuclease activity. Predicted to be involved in base-excision repair. Predicted to act upstream of or within DNA repair. Predicted to be located in chromosome. Predicted to be active in nucleus. Orthologous to human NEIL3 (nei like DNA glycosylase 3).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

1 figure from Thisse et al., 2004

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

IMAGE:6908987 (1 image)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With neil3 Human Ortholog

No data available

Associated With neil3 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Binding_site	IPR015887	DNA glycosylase/AP lyase, zinc finger domain, DNA-binding site
Domain	IPR000214	Zinc finger, DNA glycosylase/AP lyase-type
Domain	IPR001876	Zinc finger, RanBP2-type
Domain	IPR010666	Zinc finger, GRF-type
Domain	IPR012319	Formamidopyrimidine-DNA glycosylase, catalytic domain
Domain	IPR015886	DNA glycosylase/AP lyase, H2TH DNA-binding
Homologous_superfamily	IPR010979	Small ribosomal subunit protein uS13-like, H2TH
Homologous_superfamily	IPR035937	MutM-like, N-terminal
Homologous_superfamily	IPR036443	Zinc finger, RanBP2-type superfamily

Domain Details Per Protein

Protein	Length	DNA glycosylase/AP lyase, H2TH DNA-binding	DNA glycosylase/AP lyase, zinc finger domain, DNA-binding site	Formamidopyrimidine-DNA glycosylase, catalytic domain	MutM-like, N-terminal	Small ribosomal subunit protein uS13-like, H2TH	Zinc finger, DNA glycosylase/AP lyase-type	Zinc finger, GRF-type	Zinc finger, RanBP2-type	Zinc finger, RanBP2-type superfamily
UniProtKB:Q5U3G8 InterPro	550
UniProtKB:F1Q570 InterPro	568

Transcripts

Genome Browsers

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	neil3-201 (1) Ensembl	Ensembl	1,903 nt	Select Tool ZFIN BLAST
mRNA	neil3-202 (1) Ensembl	Ensembl	1,999 nt	Select Tool ZFIN BLAST
ncRNA	neil3-002 (1) Ensembl	Ensembl	825 nt	Select Tool ZFIN BLAST

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations