Gene
thg1l
- ID
- ZDB-GENE-041114-170
- Name
- tRNA-histidine guanylyltransferase 1-like
- Symbol
- thg1l Nomenclature History
- Previous Names
-
- zgc:101609
- Type
- protein_coding_gene
- Location
- Chr: 14 Mapping Details/Browsers
- Description
- Predicted to have tRNA guanylyltransferase activity. Predicted to be involved in tRNA processing. Human ortholog(s) of this gene implicated in autosomal recessive cerebellar ataxia. Orthologous to human THG1L (tRNA-histidine guanylyltransferase 1 like).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Thisse et al., 2004
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:101609 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| autosomal recessive spinocerebellar ataxia 28 | Alliance | Spinocerebellar ataxia, autosomal recessive 28 | 618800 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Thg1 C-terminal domain | tRNAHis guanylyltransferase catalytic domain | tRNAHis guanylyltransferase Thg1 | tRNAHis guanylyltransferase Thg1 superfamily |
|---|---|---|---|---|---|
|
UniProtKB:Q5U3V1
|
269 | ||||
|
UniProtKB:A0A8M6Z217
|
164 |
Interactions and Pathways
No data available
Plasmids
No data available