Gene

thg1l

ID

ZDB-GENE-041114-170

Name

tRNA-histidine guanylyltransferase 1-like

Symbol

thg1l Nomenclature History

Previous Names

zgc:101609

Type

protein_coding_gene

Location

Chr: 14 Mapping Details/Browsers

Description

Predicted to have tRNA guanylyltransferase activity. Predicted to be involved in tRNA processing. Human ortholog(s) of this gene implicated in autosomal recessive cerebellar ataxia. Orthologous to human THG1L (tRNA-histidine guanylyltransferase 1 like).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

1 figure from Thisse et al., 2004

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Thisse Expression Data

MGC:101609 (1 image)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With thg1l Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
autosomal recessive spinocerebellar ataxia 28	Alliance	Spinocerebellar ataxia, autosomal recessive 28	618800

Associated With thg1l Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR024956	tRNAHis guanylyltransferase catalytic domain
Domain	IPR025845	Thg1 C-terminal domain
Family	IPR007537	tRNAHis guanylyltransferase Thg1
Homologous_superfamily	IPR038469	tRNAHis guanylyltransferase Thg1 superfamily