Gene
fmnl2b
- ID
- ZDB-GENE-041111-182
- Name
- formin-like 2b
- Symbol
- fmnl2b Nomenclature History
- Previous Names
-
- fa31c06
- im:7143207
- wu:fa31c06
- Type
- protein_coding_gene
- Location
- Chr: 6 Mapping Details/Browsers
- Description
- Predicted to have actin filament binding activity. Predicted to be involved in cell migration; cortical actin cytoskeleton organization; and regulation of cell shape. Predicted to localize to cytosol. Is expressed in several structures, including hatching gland; heart tube; nervous system; optic cup; and solid lens vesicle. Orthologous to human FMNL2 (formin like 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 8 figures from 3 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- IMAGE:7143207 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Type | InterPro ID | Name |
---|---|---|
Domain | IPR010472 | Formin, FH3 domain |
Domain | IPR010473 | Formin, GTPase-binding domain |
Domain | IPR014767 | Diaphanous autoregulatory (DAD) domain |
Domain | IPR014768 | Rho GTPase-binding/formin homology 3 (GBD/FH3) domain |
Domain | IPR015425 | Formin, FH2 domain |
Family | IPR043592 | Formin-like protein, animal |
Homologous_superfamily | IPR011989 | Armadillo-like helical |
Homologous_superfamily | IPR016024 | Armadillo-type fold |
Homologous_superfamily | IPR042201 | Formin, FH2 domain superfamily |
Domain Details Per Protein
Protein | Length | Armadillo-like helical | Armadillo-type fold | Diaphanous autoregulatory (DAD) domain | Formin, FH2 domain | Formin, FH2 domain superfamily | Formin, FH3 domain | Formin, GTPase-binding domain | Formin-like protein, animal | Rho GTPase-binding/formin homology 3 (GBD/FH3) domain |
---|---|---|---|---|---|---|---|---|---|---|
UniProtKB:A0A8M3B3A0
|
1103 | |||||||||
UniProtKB:A0A2R8RYU9
|
1110 | |||||||||
UniProtKB:A0A8M3AT86
|
1097 | |||||||||
UniProtKB:E7F0M4
|
1104 |
Type | Name | Annotation Method | Length (nt) | Analysis |
---|---|---|---|---|
mRNA |
fmnl2b-201
(1)
|
Ensembl | 4314 nt | |
mRNA |
fmnl2b-202
(1)
|
Havana | 609 nt | |
mRNA |
fmnl2b-203
(1)
|
Havana | 2913 nt | |
mRNA |
fmnl2b-204
(1)
|
Ensembl | 4308 nt | |
mRNA |
fmnl2b-205
(1)
|
Ensembl | 4389 nt |
Interactions and Pathways
No data available
Plasmids
No data available