Gene

ino80

ID
ZDB-GENE-041014-72
Name
INO80 complex ATPase subunit
Symbol
ino80 Nomenclature History
Previous Names
  • si:ch211-244p18.3
Type
protein_coding_gene
Location
Chr: 20 Mapping Details/Browsers
Description
Predicted to contribute to 3'-5' DNA helicase activity. Predicted to be involved in DNA repair; chromatin remodeling; and regulation of transcription from RNA polymerase II promoter in response to stress. Predicted to localize to Ino80 complex. Orthologous to human INO80 (INO80 complex ATPase subunit).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
1 figure from Ding et al., 2020
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
1 Figure from Shin et al., 2021
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With ino80 Human Ortholog
No data available
Associated With ino80 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR000330 SNF2, N-terminal
Domain IPR001650 Helicase, C-terminal domain-like
Domain IPR014001 Helicase superfamily 1/2, ATP-binding domain
Domain IPR020838 DBINO domain
Domain IPR031047 DNA helicase INO80, DEAQ-box helicase domain
Domain IPR049730 SNF2/RAD5-like, C-terminal helicase domain
Family IPR050520 INO80/SWR1 chromatin remodeling helicase
Homologous_superfamily IPR027417 P-loop containing nucleoside triphosphate hydrolase
Homologous_superfamily IPR038718 SNF2-like, N-terminal domain superfamily
Domain Details Per Protein
Protein Length DBINO domain DNA helicase INO80, DEAQ-box helicase domain Helicase, C-terminal domain-like Helicase superfamily 1/2, ATP-binding domain INO80/SWR1 chromatin remodeling helicase P-loop containing nucleoside triphosphate hydrolase SNF2-like, N-terminal domain superfamily SNF2, N-terminal SNF2/RAD5-like, C-terminal helicase domain
UniProtKB:A0A8M3ARX1 1558
UniProtKB:Q5SPB7 1552
UniProtKB:A0A8M3B1Z5 1557
UniProtKB:A0A8M3AZ14 1556
Transcripts
Genome Browsers
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA ino80-201 (1) Ensembl 5,814 nt
mRNA ino80-203 (1) Ensembl 9,045 nt
mRNA ino80-204 (1) Ensembl 9,162 nt
ncRNA ino80-002 (1) Ensembl 709 nt
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations