Gene
arl2
- ID
- ZDB-GENE-041010-19
- Name
- ADP-ribosylation factor-like 2
- Symbol
- arl2 Nomenclature History
- Previous Names
-
- zgc:103658 (1)
- Type
- protein_coding_gene
- Location
- Chr: 7 Mapping Details/Browsers
- Description
- Predicted to have GTP binding activity. Predicted to be involved in positive regulation of microtubule polymerization. Predicted to localize to cytoplasm and microtubule cytoskeleton. Orthologous to human ARL2 (ADP ribosylation factor like GTPase 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Thisse et al., 2004
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:103658 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| ?Microcornea, rod-cone dystrophy, cataract, and posterior staphyloma 1 | 619082 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR005225 | Small GTP-binding domain |
| Family | IPR006689 | Small GTPase superfamily, ARF/SAR type |
| Family | IPR044612 | ADP-ribosylation factor-like protein 2/3 |
| Family | IPR045873 | ADP-ribosylation factor-like protein 2 |
| Homologous_superfamily | IPR027417 | P-loop containing nucleoside triphosphate hydrolase |
Domain Details Per Protein
| Protein | Length | ADP-ribosylation factor-like protein 2 | ADP-ribosylation factor-like protein 2/3 | P-loop containing nucleoside triphosphate hydrolase | Small GTPase superfamily, ARF/SAR type | Small GTP-binding domain |
|---|---|---|---|---|---|---|
|
UniProtKB:Q5XJ51
|
184 |
Interactions and Pathways
No data available
Plasmids
No data available